Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.44 |
| ▸ | ERBB2 | P04626 | 7/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | EPHA2 | P29317 | 3/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30140082 | 0.84 | EGFR (0.48) | EGFRERBB2HPGDHTTERBB4 | |
| SCHEMBL30140320 | 0.80 | EGFR (0.55) | EGFRERBB2 | |
| SCHEMBL30140107 | 0.79 | EGFR (0.39) | EGFRERBB2EPHA2KDREPHB4 | |
| SCHEMBL23538160 | 0.79 | EGFR (0.45) | EGFRERBB2EPHA2KDREPHB4 | |
| SCHEMBL23538163 | 0.79 | EGFR (0.45) | EGFRERBB2EPHA2KDREPHB4 | |
| SCHEMBL30140434 | 0.79 | GPR119 (0.47) | EGFRERBB2EPHA2KDREPHB4 | |
| SCHEMBL30140366 | 0.74 | GPR119 (0.37) | EGFREPHA2KDREPHB4 | |
| SCHEMBL30140353 | 0.74 | KDR (0.44) | EGFRERBB2EPHA2KDREPHB4 | |
| SCHEMBL30140262 | 0.74 | EGFR (0.37) | EGFRERBB2EPHA2KDREPHB4 | |
| SCHEMBL30140329 | 0.73 | EGFR (0.49) | EGFRERBB2ERBB4EPHA2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022266426-A1 | 6-(HETEROCYCLOALKYL-OXY)-QUINAZOLINE DERIVATIVES AND USES THEREOF | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2022-12-22 | — | — | WO | disclosed |