Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.56 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6444060 | 1.00 | PDCD1 (0.56) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL2879297 | 0.97 | ALDH1A1 (0.57) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL30873516 | 0.94 | PDCD1 (0.64) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL4944987 | 0.94 | PDCD1 (0.64) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL4045055 | 0.92 | MAOA (0.57) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL11331941 | 0.91 | PDCD1 (0.59) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL2087005 | 0.89 | ALDH1A1 (0.53) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL26481127 | 0.89 | MAOA (0.48) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL9692061 | 0.87 | ALDH1A1 (0.52) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL3961650 | 0.87 | APP (0.59) | PDCD1CD274ALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117794526-A | Compositions and methods for antioxidants and anti-inflammatory therapeutics | 阿万蒂生物科学股份有限公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-112424160-B | Novel P62 ligand compound and composition for preventing, improving or treating protein conformational diseases comprising the same | 奧土择破利悟株式会社 | 2024-03-08 | — | — | CN | disclosed |
| WO-2023288020-A1 | COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS | AVANTI BIOSCIENCES INC. (US) | 2023-01-19 | — | — | WO | disclosed |