Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.56 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30141008 | 1.00 | PDCD1 (0.56) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL2879297 | 0.97 | ALDH1A1 (0.57) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL30873516 | 0.94 | PDCD1 (0.64) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL4944987 | 0.94 | PDCD1 (0.64) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL4045055 | 0.92 | MAOA (0.57) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL11331941 | 0.91 | PDCD1 (0.59) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL2087005 | 0.89 | ALDH1A1 (0.53) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL26481127 | 0.89 | MAOA (0.48) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL4839769 | 0.87 | ALDH1A1 (0.58) | PDCD1CD274ALDH1A1MAPTCYP1A2 | |
| SCHEMBL2285030 | 0.87 | ALDH1A1 (0.52) | PDCD1CD274ALDH1A1MAPTCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6900356-B2 | Polyhydroxy curcumins having antioxidant activity | LAILA IMPEX (IN) | 2005-05-31 | — | — | US | claimed |
| US-20030216600-A1 | Novel polyhydroxy curcumins having antioxidant activity | LAILA IMPEX (IN) | 2003-11-20 | — | — | US | claimed |
| WO-2002083614-A1 | NOVEL POLYHYDROXY CURCUMINS HAVING ANTIOXIDANT ACTIVITY | LAILA, IMPEX (IN) | 2002-10-24 | — | — | WO | claimed |
| EP-3828163-B1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING PROTEINOPATHIES COMPRISING SAME | AUTOTAC INC (KR) | 2026-05-20 | — | — | EP | disclosed |
| US-12427346-B2 | P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same | AUTOTAC INC. (KR) | 2025-09-30 | — | — | US | disclosed |
| US-20240336588-A1 | COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS | AVANTI BIOSCIENCES, INC. | 2024-10-10 | — | — | US | disclosed |
| EP-4370113-A1 | COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS | Avanti Biosciences Inc. (US) | 2024-05-22 | — | — | EP | disclosed |
| WO-2023288020-A1 | COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS | AVANTI BIOSCIENCES INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| WO-2023288020-A1 | COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS | AVANTI BIOSCIENCES INC. (US) | 2023-01-19 | — | — | WO | disclosed |
| US-20210163399-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, AMELIORATING OR TREATING PROTEINOPATHIES COMPRING THE SAME | PROTECH CO., LTD. (KR) | 2021-06-03 | — | — | US | disclosed |
| US-20210163399-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, AMELIORATING OR TREATING PROTEINOPATHIES COMPRING THE SAME | PROTECH CO., LTD. (KR) | 2021-06-03 | — | — | US | disclosed |
| EP-3828163-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING PROTEINOPATHIES COMPRISING SAME | Protech Co., Ltd. (KR) | 2021-06-02 | — | — | EP | disclosed |
| EP-3828163-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING PROTEINOPATHIES COMPRISING SAME | Protech Co., Ltd. (KR) | 2021-06-02 | — | — | EP | disclosed |
| WO-2020022784-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, ALLEVIATING, OR TREATING PROTEINOPATHIES COMPRISING SAME | 주식회사 프로텍바이오 | 2020-01-30 | — | — | WO | disclosed |
| EP-2917209-B1 | 1-[1-(BENZOYL)-PYRROLIDINE-2-CARBONYL]-PYRROLIDINE-2-CARBONITRILE DERIVATIVES | UNIV BARCELONA (ES) | 2017-02-08 | — | — | EP | disclosed |
| US-6900356-B2 | Polyhydroxy curcumins having antioxidant activity | LAILA IMPEX (IN) | 2005-05-31 | — | — | US | disclosed |
| US-20030216600-A1 | Novel polyhydroxy curcumins having antioxidant activity | LAILA IMPEX (IN) | 2003-11-20 | — | — | US | disclosed |
| WO-2002083614-A1 | NOVEL POLYHYDROXY CURCUMINS HAVING ANTIOXIDANT ACTIVITY | LAILA, IMPEX (IN) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030216600-A1 | Novel polyhydroxy curcumins having antioxidant activity | DBH, KEAP1, HMOX1 | PDCD1 2310/4885CD274 2982/4885ALDH1A1 53/4885 |
| US-20210163399-A1 | NOVEL P62 LIGAND COMPOUND, AND COMPOSITION FOR PREVENTING, AMELIORATING OR TREATING PROTEINOPATHIES COMPRING THE SAME | SQSTM1, ATG7, BECN1 | PDCD1 1779/4885CD274 2279/4885ALDH1A1 4667/4885 |
| US-12427346-B2 | P62 ligand compound, and composition for preventing, ameliorating or treating proteinopathies comprising the same | SQSTM1, ATG7, BECN1 | PDCD1 1514/4885CD274 2018/4885ALDH1A1 4677/4885 |
| US-20240336588-A1 | COMPOSITIONS AND METHODS FOR ANTIOXIDANT AND ANTI-INFLAMMATORY THERAPEUTICS | MPO, GPX4, GPX1 | PDCD1 2253/4885CD274 2429/4885ALDH1A1 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.