Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | WNT1 | P04628 | 5/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 5/20 | 0.62 |
| ▸ | RAD52 | P43351 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30142268 | 0.93 | WNT1 (0.64) | WNT1DYRK1ARAD52ALDH1A1SMN1; SMN2 | |
| SCHEMBL30142319 | 0.85 | RAB9A (0.48) | WNT1DYRK1AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30142240 | 0.83 | SMN1; SMN2 (0.44) | WNT1DYRK1AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30142244 | 0.82 | WNT1 (0.49) | WNT1DYRK1AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30142245 | 0.82 | WNT1 (0.49) | WNT1DYRK1AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30142384 | 0.80 | DYRK1A (0.51) | WNT1DYRK1AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30142285 | 0.79 | YTHDC1 (0.59) | WNT1DYRK1AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30142265 | 0.79 | RAB9A (0.43) | WNT1DYRK1AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL30142248 | 0.79 | RAB9A (0.43) | WNT1DYRK1AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL17095647 | 0.77 | DYRK1A (1.00) | WNT1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220388964-A1 | (AZA)INDAZOLYL-ARYL SULFONAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | HIBERCELL, INC. | 2022-12-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220388964-A1 | (AZA)INDAZOLYL-ARYL SULFONAMIDE AND RELATED COMPOUNDS AND THEIR USE IN TREATING MEDICAL CONDITIONS | EIF2AK4, GCN1, GNAI2 | WNT1 2112/4885DYRK1A 3529/4885RAD52 3120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.