Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | FLT4 | P35916 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 1/20 | 0.45 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30142965 | 0.89 | SMN1; SMN2 (0.51) | HDAC3HDAC1HDAC4HDAC7HDAC2 | |
| SCHEMBL6615293 | 0.81 | CYP11B1 (0.57) | SMN1; SMN2NAMPTKMT2AMEN1RAB9A | |
| SCHEMBL11166906 | 0.81 | CDK2 (0.52) | CDK2FLT4SMN1; SMN2HTTKEAP1 | |
| SCHEMBL11160665 | 0.80 | LMNA (0.50) | CDK2FLT4SMN1; SMN2KEAP1NFE2L2 | |
| SCHEMBL11166666 | 0.78 | MEN1 (0.51) | CDK2FLT4SMN1; SMN2KEAP1NFE2L2 | |
| SCHEMBL8917912 | 0.78 | IKBKB (0.63) | CDK2FLT4NAMPTKEAP1NFE2L2 | |
| SCHEMBL9147482 | 0.78 | BCL6 (0.53) | CDK2FLT4NAMPTKEAP1NFE2L2 | |
| SCHEMBL14212483 | 0.77 | NOTUM (0.51) | CDK2FLT4SMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL14234251 | 0.76 | CDK2 (0.42) | CDK2FLT4KEAP1NFE2L2ALDH1A1 | |
| SCHEMBL11160336 | 0.76 | KMT2A (0.53) | CDK2FLT4NAMPTKEAP1NFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848506-B | Biphenyl urea compound and pharmaceutical composition, preparation method and application thereof | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |