Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 3/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | FDPS | P14324 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856127 | 1.00 | CHRNB2 (0.48) | CHRNB2CHRNA4NAPRTCYP1A2CYP2D6 | |
| Tetrahydrofuran SCHEMBL28632646 | 0.87 | ALDH1A1 (0.42) | CHRNB2CHRNA4NAPRTCYP1A2CYP2D6 | |
| SCHEMBL17168324 | 0.81 | CHRNA7 (0.52) | CHRNB2CHRNA4NAPRTCYP1A2CYP2D6 | |
| SCHEMBL1027113 | 0.81 | MIF (0.59) | CHRNB2CHRNA4NAPRTCYP1A2CYP2D6 | |
| Bromide SCHEMBL2337339 | 0.79 | MIF (0.57) | CHRNB2CHRNA4NAPRTCYP1A2CYP2D6 | |
| SCHEMBL3936550 | 0.79 | CYP1A2 (0.58) | CHRNB2CHRNA4NAPRTCYP1A2CYP2D6 | |
| SCHEMBL18500410 | 0.78 | — | — | |
| SCHEMBL11033045 | 0.75 | LOXL2 (0.41) | CYP1A2CYP2D6FDPSCYP3A4CYP2C9 | |
| SCHEMBL8193469 | 0.75 | NAAA (0.44) | CHRNB2CHRNA4NAPRTCYP1A2CYP2D6 | |
| SCHEMBL1172136 | 0.74 | MIF (0.60) | CYP2A6CYP3A4TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111848506-B | Biphenyl urea compound and pharmaceutical composition, preparation method and application thereof | 中国药科大学 | 2023-01-31 | — | — | CN | disclosed |