SCHEMBL30145447

SCHEMBL30145447

CC(C)NCCCNCC(O)Cn1c2ccc(F)cc2c2cc(F)ccc21

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ CRY2 Q49AN0 18/20 0.57
▸ PER2 O15055 16/20 0.57
▸ CRY1 Q16526 10/20 0.57
▸ DNM1 Q05193 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17138574 1.00 CRY2 (0.57) CRY2PER2CRY1DNM1
SCHEMBL17138632 0.84 PER2 (0.60) CRY2PER2CRY1DNM1
SCHEMBL17138635 0.84 PER2 (0.60) CRY2PER2CRY1DNM1
SCHEMBL29558380 0.84 PER2 (0.60) CRY2PER2CRY1DNM1
SCHEMBL17138871 0.82 DNM1 (0.57) CRY2PER2CRY1DNM1
SCHEMBL30145538 0.82 DNM1 (0.57) CRY2PER2CRY1DNM1
SCHEMBL28406050 0.82 CRY2 (0.64) CRY2PER2CRY1DNM1
SCHEMBL29448065 0.82 CRY2 (0.64) CRY2PER2CRY1DNM1
SCHEMBL30145432 0.82 PER2 (0.50) CRY2PER2CRY1
SCHEMBL17138604 0.82 PER2 (0.50) CRY2PER2CRY1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240190837-A1 CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS SYCHRONICITY PHARMA INC (US) 2024-06-13 — — US disclosed
US-20220411399-A1 CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS SYCHRONICITY PHARMA INC (US) 2022-12-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220411399-A1 CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS CRY1, CRY2, HCCS CRY2 2/4885PER2 188/4885CRY1 1/4885
US-20240190837-A1 CARBAZOLE-CONTAINING AMIDES, CARBAMATES, AND UREAS AS CRYPTOCHROME MODULATORS CRY1, CRY2, HCCS CRY2 2/4885PER2 188/4885CRY1 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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