Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | LTA4H | P09960 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28251675 | 0.79 | CYP1A2 (0.42) | LMNAALDH1A1TSHRCYP3A4MEN1 | |
| SCHEMBL2429098 | 0.78 | CYP1A2 (0.41) | LMNAALDH1A1TSHRCYP3A4MEN1 | |
| Hydrochloric Acid SCHEMBL7659960 | 0.78 | CYP1A2 (0.41) | LMNAALDH1A1TSHRCYP3A4MEN1 | |
| SCHEMBL4409381 | 0.76 | NPC1 (0.41) | LMNAALDH1A1TSHRCYP3A4MEN1 | |
| SCHEMBL3016798 | 0.74 | CA2 (0.43) | MEN1KMT2ACLK4SYKGSK3B | |
| SCHEMBL27491044 | 0.72 | HAVCR2 (0.37) | LMNAALDH1A1TSHRCYP3A4MEN1 | |
| SCHEMBL3014786 | 0.69 | SYK (0.47) | ALDH1A1TSHRCYP3A4MEN1KMT2A | |
| SCHEMBL795951 | 0.69 | L3MBTL1 (0.35) | LMNAALDH1A1TSHRCYP3A4MEN1 | |
| SCHEMBL10411688 | 0.68 | SYK (0.58) | LMNATSHRCYP3A4MEN1KMT2A | |
| SCHEMBL796979 | 0.68 | FDPS (0.32) | TSHRLTA4HKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | PALAU PHARMA, S.A. (ES) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | JAK3, JAK1, JAK2 | LMNA 4233/4885ALDH1A1 1686/4885TSHR 3018/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.