Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terephthalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 16/20 | 0.45 |
| ▸ | CA1 | P00915 | 15/20 | 0.45 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aminobenzoic Acid SCHEMBL5928100 | 0.91 | LMNA (0.43) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Benzoic Acid SCHEMBL2196273 | 0.90 | CA2 (0.57) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Isophthalic Acid SCHEMBL30148147 | 0.85 | KMT2A (0.41) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Benzoic Acid SCHEMBL16106190 | 0.83 | CA2 (0.53) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Terephthalic Acid SCHEMBL11804306 | 0.83 | CA2 (0.48) | CA2CA1CA4 | |
| Beta-Naphtoic Acid SCHEMBL28561493 | 0.82 | CES2 (0.47) | MEN1KMT2ACYP3A4 | |
| Benzoic Acid SCHEMBL20919826 | 0.82 | CA2 (0.47) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Phthalic Acid SCHEMBL7100569 | 0.80 | MEN1 (0.44) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Gallic Acid SCHEMBL27148640 | 0.80 | LMNA (0.40) | MEN1LMNAKMT2ACYP3A4SLC5A7 | |
| Terephthalic Acid SCHEMBL106549 | 0.79 | CA2 (0.59) | CA2CA1CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11560579-B2 | Method for pretreating lignocellulosic biomass | Petróleo Brasileiro S.A.—Petrobras (BR) | 2023-01-24 | — | — | US | claimed |
| US-11560579-B2 | Method for pretreating lignocellulosic biomass | Petróleo Brasileiro S.A.—Petrobras (BR) | 2023-01-24 | — | — | US | disclosed |