Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EZH2 | Q15910 | 17/20 | 0.39 |
| ▸ | EHMT2 | Q96KQ7 | 2/20 | 0.39 |
| ▸ | EED | O75530 | 3/20 | 0.35 |
| ▸ | RBBP4 | Q09028 | 3/20 | 0.35 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.35 |
| ▸ | AEBP2 | Q6ZN18 | 3/20 | 0.35 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30148789 | 0.79 | MAPT (0.37) | EZH2EHMT2EEDRBBP4SUZ12 | |
| SCHEMBL28523974 | 0.77 | CDK1 (0.57) | — | |
| SCHEMBL23683275 | 0.75 | CDK1 (0.41) | TMIGD3HTR2CHTR2B | |
| SCHEMBL30148806 | 0.75 | CDK1 (0.45) | EZH2 | |
| SCHEMBL30148823 | 0.74 | CTSL (0.45) | EZH2 | |
| SCHEMBL28744768 | 0.73 | EZH2 (0.63) | EZH2EHMT2EEDRBBP4SUZ12 | |
| SCHEMBL31670501 | 0.73 | EZH2 (0.38) | EZH2EHMT2EEDRBBP4SUZ12 | |
| SCHEMBL20119692 | 0.72 | SMN1; SMN2 (0.34) | TMIGD3HTR2CHTR2B | |
| SCHEMBL7110908 | 0.72 | XDH (0.41) | TMIGD3HTR2CHTR2B | |
| SCHEMBL30785590 | 0.71 | EZH2 (0.37) | EZH2EHMT2EEDRBBP4SUZ12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903289-B | Purine-aminomethyl-pyridone derivative, preparation method and application thereof | 四川大学 | 2023-02-03 | — | — | CN | disclosed |