Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | EZH2 | Q15910 | 13/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 3/20 | 0.35 |
| ▸ | RBBP4 | Q09028 | 3/20 | 0.35 |
| ▸ | SUZ12 | Q15022 | 3/20 | 0.35 |
| ▸ | AEBP2 | Q6ZN18 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30148788 | 0.79 | EZH2 (0.39) | EZH2EHMT2EEDRBBP4SUZ12 | |
| SCHEMBL30148807 | 0.74 | NPC1 (0.45) | EZH2SMN1; SMN2RXFP1ADORA1 | |
| SCHEMBL6228309 | 0.69 | MEN1 (0.38) | MAPTPOLBMAPK1KMT2AALDH1A1 | |
| SCHEMBL17450144 | 0.68 | AURKA (0.41) | KMT2AALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL16146855 | 0.68 | ALDH1A1 (0.44) | POLBMAPK1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL13906499 | 0.65 | TMIGD3 (0.42) | MAPTPOLBSMN1; SMN2ADORA1 | |
| SCHEMBL16146146 | 0.64 | KDM4E (0.44) | MAPTPOLBKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL16146273 | 0.64 | MAP4K4 (0.44) | MAPTPOLBKMT2ASMN1; SMN2MEN1 | |
| SCHEMBL20119609 | 0.64 | ADORA3 (0.49) | MAPTPOLBKMT2AALDH1A1LMNA | |
| SCHEMBL16145744 | 0.63 | MAP4K4 (0.41) | MAPK1KMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110903289-B | Purine-aminomethyl-pyridone derivative, preparation method and application thereof | 四川大学 | 2023-02-03 | — | — | CN | disclosed |