Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 4/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | PGK1 | P00558 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 2/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12963516 | 0.87 | HTT (0.44) | XDHADORA3SMN1; SMN2TMIGD3HTR2C | |
| SCHEMBL9882917 | 0.83 | HDAC1 (0.42) | XDHLMNASMN1; SMN2CDK1 | |
| SCHEMBL12933326 | 0.83 | XDH (0.39) | XDHSMN1; SMN2TMIGD3HTR2CHTR2B | |
| SCHEMBL16146383 | 0.81 | PGK1 (0.36) | ADORA3DRD1PGK1CDK1 | |
| SCHEMBL16146880 | 0.81 | CRHR1 (0.36) | ADORA3DRD1PGK1SMN1; SMN2CDK1 | |
| SCHEMBL130696 | 0.81 | XDH (0.57) | XDHADORA3ADORA1 | |
| SCHEMBL14196060 | 0.81 | XDH (0.36) | XDHADORA3ADORA1SMN1; SMN2TMIGD3 | |
| SCHEMBL28637054 | 0.81 | CYP3A4 (0.44) | XDHSMN1; SMN2TMIGD3HTR2CHTR2B | |
| SCHEMBL21788563 | 0.80 | SLC29A1 (0.39) | XDHLMNAADORA3ADORA1SMN1; SMN2 | |
| SCHEMBL16145919 | 0.80 | ADORA3 (0.32) | ADORA3DRD1PGK1CDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105159-A1 | LIGANDS OF THE M6A-RNA READERS | UNIVERSITY OF ZURICH (CH) | 2024-05-23 | — | — | WO | disclosed |
| CN-1213047-C | Puring derivatives inhibitors of tyrosine kinase SYK | NOVARTIS AG (CH) | 2005-08-03 | — | — | CN | disclosed |
| EP-1200435-B1 | PURINE DERIVATIVES INHIBITORS OF TYROSINE PROTEIN KINASE SYK | NOVARTIS AG (CH) | 2003-10-01 | — | — | EP | disclosed |
| US-6589950-B1 | Treatment of inflammatory or obstructive airways disease for respiratory system disorders | NOVARTIS AG (CH) | 2003-07-08 | — | — | US | disclosed |
| WO-2003024448-A2 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE, INC. (CA) | 2003-03-27 | — | — | WO | disclosed |
| CN-1365360-A | purine derivative inhibitors of tyrosine protein kinase SYK | NOVARTIS AG (CH) | 2002-08-21 | — | — | CN | disclosed |
| EP-1200435-A1 | PURINE DERIVATIVES INHIBITORS OF TYROSINE PROTEIN KINASE SYK | Novartis AG (CH) | 2002-05-02 | — | — | EP | disclosed |
| WO-2001009134-A1 | PURINE DERIVATIVES INHIBITORS OF TYROSINE PROTEIN KINASE SYK | NOVARTIS AG (CH) | 2001-02-08 | — | — | WO | disclosed |