SCHEMBL3014879

SCHEMBL3014879

Nc1cccc(Oc2ccccc2C(=O)O)c1N

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 2/20 0.57
MMP2 P08253 1/20 0.50
KDM4E B2RXH2 9/20 0.47
HSD17B10 Q99714 6/20 0.47
ALDH1A1 P00352 6/20 0.47
HPGD P15428 5/20 0.47
ESR1 P03372 1/20 0.47
ITGB3 P05106 1/20 0.47
ITGA2B P08514 1/20 0.47
HMGB1 P09429 1/20 0.47
TSHR P16473 1/20 0.47
GGT1 P19440 1/20 0.47
PTGS1 P23219 1/20 0.47
PTGS2 P35354 1/20 0.47
BLM P54132 1/20 0.47
NAPRT Q6XQN6 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
MAPT P10636 2/20 0.46
CTNNB1 P35222 1/20 0.46
USP2 O75604 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2191708 0.87 HTT (0.62) HTTMMP2KDM4EHSD17B10ALDH1A1
SCHEMBL6310272 0.86 HTT (0.57) HTTKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL19858470 0.85 MAPT (0.59) HTTHSD17B10ALDH1A1MAPTCTNNB1
SCHEMBL12217892 0.85 G6PD (0.62) HTTMMP2KDM4EHSD17B10ALDH1A1
SCHEMBL6310285 0.84 HTT (0.48) HTTMMP2KDM4EHSD17B10ALDH1A1
SCHEMBL30314458 0.83 G6PD (0.59) HTTMMP2KDM4EHSD17B10ALDH1A1
SCHEMBL7716207 0.83 G6PD (0.59) HTTMMP2KDM4EHSD17B10ALDH1A1
SCHEMBL29682980 0.83 HTT (0.77) HTTKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL446113 0.83 HTT (0.77) HTTKDM4EHSD17B10ALDH1A1HPGD
SCHEMBL8434168 0.81 HTT (0.81) HTTKDM4EHSD17B10ALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8394878-B2 Hyperbranched organic modifier, method of preparing thereof and organo-modified clay using the same CHEIL INDUSTRIES INC. (KR) 2013-03-12 US disclosed
US-20100190905-A1 Hyperbranched Organic Modifier, Method of Preparing Thereof and Organo-Modified Clay Using the Same CHEIL INDUSTRIES INC. (KR) 2010-07-29 US disclosed
WO-2009005190-A1 HYPERBRANCHED ORGANIC MODIFIER, METHOD OF PREPARING THEREOF AND ORGANO-MODIFIED CLAY USING THE SAME CHEIL INDUSTRIES INC. (KR) 2009-01-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100190905-A1 Hyperbranched Organic Modifier, Method of Preparing Thereof and Organo-Modified Clay Using the Same HAO2, HAAO, EHMT2 HTT 919/4885MMP2 4674/4885KDM4E 563/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.