Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.34 |
| ▸ | MAP2 | P11137 | 2/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK8 | P49336 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 4/20 | 0.33 |
| ▸ | PKM | P14618 | 2/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30149138 | 0.77 | ALDH1A1 (0.52) | MAP2ARKDM4EMAPTALDH1A1 | |
| SCHEMBL29613820 | 0.72 | KDM4E (0.54) | MAPK8MAPK10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL15859711 | 0.67 | L3MBTL1 (0.44) | MAPK8MAPK10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL628125 | 0.65 | MAPK1 (0.54) | CYP1A2CYP2C9CYP2C19ARKDM4E | |
| SCHEMBL1633542 | 0.64 | CA12 (0.44) | CYP1A2CYP2C9CYP2C19PKMKDM4E | |
| Hydrochloric Acid SCHEMBL7840484 | 0.64 | MAPK1 (0.53) | CYP1A2CYP2C9CYP2C19ARKDM4E | |
| SCHEMBL5500439 | 0.64 | NNMT (0.41) | MAPK8MAPK10CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10664081 | 0.64 | L3MBTL1 (0.39) | L3MBTL1KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL9388313 | 0.63 | NQO2 (0.43) | POLBARKDM4EL3MBTL1KMT2A | |
| SCHEMBL9789186 | 0.62 | CA12 (0.50) | MAPK8MAPK10POLBKDM4EL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11541034-B2 | Nitrile-containing antiviral compounds | PFIZER INC. (US) | 2023-01-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11541034-B2 | Nitrile-containing antiviral compounds | ACE2, NOS2, EIF2AK2 | MAPK8 4415/4885MAPK10 3249/4885MAP2 4264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.