Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.48 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.35 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL844273 | 1.00 | ERN1 (0.48) | ERN1NFE2L2NPC1POLBGAA | |
| SCHEMBL30800801 | 0.84 | ERN1 (0.48) | ERN1NFE2L2NPC1POLBGAA | |
| SCHEMBL9274800 | 0.84 | ERN1 (0.48) | ERN1NFE2L2NPC1POLBGAA | |
| SCHEMBL25398893 | 0.80 | NFE2L2 (0.39) | ERN1NFE2L2NPC1POLBGAA | |
| SCHEMBL13126151 | 0.80 | ALOX5 (0.36) | ERN1NFE2L2CCNT1CDK9HASPIN | |
| SCHEMBL3663643 | 0.80 | NFE2L2 (0.36) | ERN1NFE2L2NPC1POLBGAA | |
| SCHEMBL16446421 | 0.77 | NFE2L2 (0.40) | ERN1NFE2L2NPC1POLBGAA | |
| SCHEMBL14686341 | 0.77 | NFE2L2 (0.46) | ERN1NFE2L2NPC1POLBSLC22A12 | |
| SCHEMBL29988644 | 0.75 | NFE2L2 (0.40) | ERN1NFE2L2NPC1POLBGAA | |
| SCHEMBL20772453 | 0.73 | KIF11 (0.41) | NPC1POLBGAASLC22A12L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736178-B | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2025-03-21 | — | — | CN | disclosed |
| CN-117736178-A | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-117510468-A | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2024-02-06 | — | — | CN | disclosed |
| CN-117466868-A | Dual MAGL and FAAH inhibitors | 灵北拉荷亚研究中心公司 | 2024-01-30 | — | — | CN | disclosed |
| WO-2022221686-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2022-10-20 | — | — | WO | disclosed |