SCHEMBL30150865

SCHEMBL30150865

COC(=O)C(C)(F)N(Cc1ccccc1)Cc1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTRB1 P17538 1/20 0.50
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
NPC1 O15118 2/20 0.45
RAB9A P51151 2/20 0.45
KCNN4 O15554 1/20 0.43
CYP2C19 P33261 1/20 0.43
RECQL P46063 1/20 0.43
RIPK1 Q13546 2/20 0.43
AKT1 P31749 2/20 0.43
MTOR P42345 1/20 0.43
HTT P42858 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
CA12 O43570 1/20 0.41
CA9 Q16790 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22095153 0.83 CYP2C19 (0.47) MEN1KMT2ANPC1RAB9ACYP2C19
SCHEMBL5505659 0.76 CTRB1 (0.49) CTRB1MEN1KMT2ANPC1RAB9A
SCHEMBL22982786 0.75 NPC1 (0.50) CTRB1MEN1KMT2ANPC1RAB9A
SCHEMBL4154050 0.75 CTRB1 (0.48) CTRB1MEN1KMT2ANPC1RAB9A
SCHEMBL29151949 0.75 TDP1 (0.50) CTRB1MEN1KMT2ANPC1RAB9A
SCHEMBL28808224 0.75 CTRB1 (0.50) CTRB1MEN1KMT2AKCNN4CYP2C19
SCHEMBL27893366 0.74 MEN1 (0.44) MEN1KMT2AHTTL3MBTL1
SCHEMBL28646100 0.74 KDM4A (0.42) CTRB1MEN1KMT2ANPC1RAB9A
SCHEMBL16884070 0.73 LMNA (0.49) NPC1RAB9ARECQLL3MBTL1
SCHEMBL21758682 0.73 LTA4H (0.46) CTRB1MEN1KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108341752-B Amine compound for inhibiting SSAO/VAP-1 and application thereof in medicine 广东东阳光药业有限公司 2022-12-23 CN disclosed