Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LCK | P06239 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ERN1 | O75460 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL336990 | 0.84 | ALDH1A1 (0.53) | GAAMAPTCA2CA12CA1 | |
| SCHEMBL30786420 | 0.84 | ALDH1A1 (0.53) | GAAMAPTCA2CA12CA1 | |
| SCHEMBL79989 | 0.82 | KDM4E (0.64) | GAAMAPTCA2CA12CA1 | |
| SCHEMBL5595306 | 0.82 | LCK (0.55) | LCKPARP1GAAMAPTCA2 | |
| SCHEMBL29476052 | 0.82 | KDM4E (0.64) | GAAMAPTCA2CA12CA1 | |
| Protocatechuamide SCHEMBL1128716 | 0.81 | LCK (0.65) | LCKPARP1GAAMAPTCA2 | |
| SCHEMBL1428434 | 0.81 | ALDH1A1 (0.49) | LCKPARP1MAPTALDH1A1HSD17B10 | |
| SCHEMBL8412857 | 0.81 | ALDH1A1 (0.49) | LCKPARP1MAPTALDH1A1HSD17B10 | |
| SCHEMBL9307729 | 0.80 | KDM4E (0.61) | GAAMAPTCA2CA12CA1 | |
| SCHEMBL3287715 | 0.80 | PRKCI (0.58) | GAAMAPTCA2CA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103288757-B | Preparation method of 6-amino-7-hydroxyl-3,4-dihydroquinazoline-4-ketone | SUZHOU MINGRUI PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-07-01 | — | — | CN | claimed |
| CN-103265497-B | Intermediate compound 4-chloro-6-amino-7-hydroxyquinazoline required for synthesis of tinib antineoplastic drug and preparation method thereof | SUZHOU MIRACPHARMA TECHNOLOGY CO LTD | 2014-11-26 | — | — | CN | claimed |
| CN-103288757-A | Preparation method of 6-amino-7-hydroxyl-3,4-dihydroquinazoline-4-ketone | SUZHOU MINGRUI PHARMACEUTICAL TECHNOLOGY CO LTD | 2013-09-11 | — | — | CN | claimed |
| CN-103265497-A | Intermediate compound 4-chloro-6-amino-7-hydroxyquinazoline required for synthesis of tinib antineoplastic drug and preparation method thereof | SUZHOU MINGYUE MEDICAL TECHNOLOGY CO LTD | 2013-08-28 | — | — | CN | claimed |
| EP-3383854-B1 | WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF | ALCON INC (CH) | 2021-03-03 | — | — | EP | disclosed |
| US-10301598-B2 | Low-molecular-compound for improving production, maintenance and proliferation of pluripotent stem cells, composition comprising the same, and culture method | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2019-05-28 | — | — | US | disclosed |
| US-20170159023-A1 | NOVEL LOW-MOLECULAR-COMPOUND FOR IMPROVING PRODUCTION, MAINTENANCE AND PROLIFERATION OF PLURIPOTENT STEM CELLS, COMPOSITION COMPRISING THE SAME, AND CULTURE METHOD | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2017-06-08 | — | — | US | disclosed |
| WO-2017093835-A1 | WATER-SOLUBLE UV-ABSORBING COMPOUNDS AND USES THEREOF | NOVARTIS AG (CH) | 2017-06-08 | — | — | WO | disclosed |
| EP-2774918-B1 | NOVEL LOW-MOLECULAR WEIGHT COMPOUND FOR PROMOTING PLURIPOTENT STEM CELL GENERATION, MAINTENANCE, AND PROLIFERATION, AND COMPOSITION AND CULTURING METHOD CONTAINING SAME | KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR) | 2017-03-22 | — | — | EP | disclosed |
| US-9587225-B2 | Low-molecular-compound for improving production, maintenance and proliferation of pluripotent stem cells, composition comprising the same, and culture method | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2017-03-07 | — | — | US | disclosed |
| CN-103288757-B | Preparation method of 6-amino-7-hydroxyl-3,4-dihydroquinazoline-4-ketone | SUZHOU MINGRUI PHARMACEUTICAL TECHNOLOGY CO LTD | 2015-07-01 | — | — | CN | disclosed |
| US-20150159142-A1 | NOVEL LOW-MOLECULAR-COMPOUND FOR IMPROVING PRODUCTION, MAINTENANCE AND PROLIFERATION OF PLURIPOTENT STEM CELLS, COMPOSITION COMPRISING THE SAME, AND CULTURE METHOD | Korea Reasearch Institute of Bioscience and Biotechnology (KR) | 2015-06-11 | — | — | US | disclosed |
| US-4563409-A | ELECTROGRAPHY | HOGOHAYA CHEMICAL CO., LTD. (JP) | 1986-01-07 | — | — | US | disclosed |
| EP-0141377-A2 | Metal complexes | HODOGAYA CHEMICAL CO., LTD. (JP) | 1985-05-15 | — | — | EP | disclosed |
| US-4141890-A | FIBER-REACTIVE | CIBA-GEIGY CORPORATION (US) | 1979-02-27 | — | — | US | disclosed |
| US-RE29585-E | DYEING WOOL | CIBA-GEIGY CORPORATION (US) | 1978-03-21 | — | — | US | disclosed |
| US-4067864-A | FOR CELLULOSE OR POLYAMIDES | CIBA-GEIGY AG (CH) | 1978-01-10 | — | — | US | disclosed |
| US-4039523-A | YELLOW | CIBA-GEIGY AG (CH) | 1977-08-02 | — | — | US | disclosed |
| US-4017477-A | 3-Halogeno-6-hydroxy-pyridone-(2) azo dyestuffs | CIBA-GEIGY AG (CH) | 1977-04-12 | — | — | US | disclosed |
| US-3971738-A | Heavy metal complexes of azo compounds containing a halogeno-2,3-dihydroxy pyridine coupling component | CIBA-GEIGY AG (CH) | 1976-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150159142-A1 | NOVEL LOW-MOLECULAR-COMPOUND FOR IMPROVING PRODUCTION, MAINTENANCE AND PROLIFERATION OF PLURIPOTENT STEM CELLS, COMPOSITION COMPRISING THE SAME, AND CULTURE METHOD | MYC, MYCBP, HES1 | LCK 4610/4885PARP1 1057/4885GAA 4180/4885 |
| US-10301598-B2 | Low-molecular-compound for improving production, maintenance and proliferation of pluripotent stem cells, composition comprising the same, and culture method | AANAT, MKI67, VIM | LCK 4565/4885PARP1 385/4885GAA 4495/4885 |
| US-20170159023-A1 | NOVEL LOW-MOLECULAR-COMPOUND FOR IMPROVING PRODUCTION, MAINTENANCE AND PROLIFERATION OF PLURIPOTENT STEM CELLS, COMPOSITION COMPRISING THE SAME, AND CULTURE METHOD | AANAT, MKI67, ACP1 | LCK 4597/4885PARP1 658/4885GAA 4400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.