SCHEMBL301540

SCHEMBL301540

Cc1ccc(C(=O)OCC(C)C)c(C(=O)OCC(C)C)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.66
TSHR P16473 4/20 0.66
MAPT P10636 2/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
HTT P42858 2/20 0.47
SMN1; SMN2 Q16637 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
KDM4E B2RXH2 1/20 0.47
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
TP53 P04637 1/20 0.46
NPY1R P25929 1/20 0.46
NPY2R P49146 1/20 0.46
ATM Q13315 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
MAPK1 P28482 1/20 0.43
CACNA1F O60840 4/20 0.42
CACNA1D Q01668 4/20 0.42
CACNA1S Q13698 4/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4628668 0.95 ALDH1A1 (0.60) ALDH1A1TSHRMAPTNPC1RAB9A
SCHEMBL4626667 0.89 TSHR (0.55) ALDH1A1TSHRSMN1; SMN2TDP1KDM4E
SCHEMBL30320099 0.88 ALDH1A1 (0.59) ALDH1A1TSHRMAPTNPC1RAB9A
SCHEMBL7512802 0.87 ALDH1A1 (0.57) ALDH1A1TSHRMAPTNPC1RAB9A
SCHEMBL5696011 0.87 ALDH1A1 (0.57) ALDH1A1TSHRMAPTNPC1RAB9A
SCHEMBL29196239 0.85 ALDH1A1 (0.56) ALDH1A1TSHRMAPTHTTSMN1; SMN2
SCHEMBL29196252 0.84 ALDH1A1 (0.54) ALDH1A1TSHRMAPTNPC1RAB9A
SCHEMBL4856552 0.84 ALDH1A1 (0.54) ALDH1A1TSHRMAPTNPC1RAB9A
SCHEMBL827863 0.83 TSHR (0.70) ALDH1A1TSHRMAPTNPC1RAB9A
SCHEMBL828419 0.83 ALDH1A1 (0.66) ALDH1A1TSHRMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115926331-B Polybutene-1 alloy and preparation method thereof 中国石油天然气股份有限公司 2025-02-11 CN claimed
CN-114805647-B Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2024-03-29 CN claimed
CN-115926331-A Polybutene-1 alloy and preparation method thereof 中国石油天然气股份有限公司 2023-04-07 CN claimed
CN-114805647-A Catalyst composition for olefin polymerization and application thereof 北京肯佰恩科技发展有限公司 2022-07-29 CN claimed
CN-111269341-A Catalyst for synthesizing high isotactic polybutene and its prepn 青岛科技大学 2020-06-12 CN claimed
CN-111234075-A Catalyst for synthesizing alloy in polybutylene kettle, preparation method and application thereof 青岛科技大学 2020-06-05 CN claimed
CN-103288993-B Spherical polybutylene-1 with high isotacticity and preparation method thereof UNIV QINGDAO SCIENCE & TECHNOLOGY 2015-06-03 CN claimed
CN-104371051-A Catalyst for polymerizing butene-1, preparation and application thereof PETROCHINA CO LTD 2015-02-25 CN claimed
CN-103288993-A Spherical polybutylene-1 with high isotacticity and preparation method thereof UNIV QINGDAO SCIENCE & TECHNOLOGY 2013-09-11 CN claimed
CN-101914172-B Spherical catalyst for 1-butene polymerization as well as preparation method and application thereof UNIV HEBEI TECHNOLOGY 2012-07-25 CN claimed
CN-101914172-A Spherical catalyst for 1-butene polymerization as well as preparation method and application thereof UNIV HEBEI TECHNOLOGY 2010-12-15 CN claimed
US-6770586-B2 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD. (JP) 2004-08-03 US claimed
CN-115926331-B Polybutene-1 alloy and preparation method thereof 中国石油天然气股份有限公司 2025-02-11 CN disclosed
US-12060378-B2 Solid catalyst component for olefin polymerization, method for producing solid catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization and method for producing polymer of olefin TOHO TITANIUM CO., LTD. (JP) 2024-08-13 US disclosed
US-20240218087-A1 SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFIN, CATALYST FOR POLYMERIZATION OF OLEFIN, METHOD FOR PRODUCING POLYMER OF OLEFIN, POLYMER OF OLEFIN, METHOD FOR PRODUCING PROPYLENE-BASED BLOCK COPOLYMER, AND PROPYLENE-BASED BLOCK COPOLYMER TOHO TITANIUM CO., LTD. (JP) 2024-07-04 US disclosed
EP-4349874-A1 OLEFIN POLYMERIZATION SOLID CATALYST COMPONENT, OLEFIN POLYMERIZATION CATALYST, MANUFACTURING METHOD FOR OLEFIN POLYMER, OLEFIN POLYMER, MANUFACTURING METHOD FOR PROPYLENE-BASED BLOCK COPOLYMER, AND PROPYLENE-BASED BLOCK COPOLYMER TOHO TITANIUM CO., LTD. (JP) 2024-04-10 EP disclosed
US-20030130109-A1 Solid catalyst component and catalyst for olefins polymerization TOHO TITANIUM CO., LTD (JP) 2003-07-10 US disclosed
US-20030036594-A1 Phthalic diester derivatives and electron donors TOHO TITANIUM CO., LTD. (JP) 2003-02-20 US disclosed
EP-1209172-A1 SOLID CATALYST COMPONENT AND CATALYST FOR OLEFIN POLYMERIZATION Toho Titanium Co., Ltd. (JP) 2002-05-29 EP disclosed
EP-1188739-A1 PHTHALIC DIESTER DERIVATIVES AND ELECTRON DONORS TOHO TITANIUM CO., LTD. (JP) 2002-03-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12060378-B2 Solid catalyst component for olefin polymerization, method for producing solid catalyst component for olefin polymerization, method for producing catalyst for olefin polymerization and method for producing polymer of olefin EEF2, ELL, POF1B ALDH1A1 3897/4885TSHR 3311/4885MAPT 2131/4885
US-20030036594-A1 Phthalic diester derivatives and electron donors HPD, ETFA, PPOX ALDH1A1 725/4885TSHR 4817/4885MAPT 814/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.