SCHEMBL93223

SCHEMBL93223

Cc1cccc(C(=O)Cl)c1C

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.49
ESR2 Q92731 1/20 0.49
ALDH1A1 P00352 4/20 0.47
HSD17B10 Q99714 3/20 0.47
KDM4E B2RXH2 2/20 0.47
HPGD P15428 2/20 0.47
KMT2A Q03164 3/20 0.46
TRPA1 O75762 2/20 0.46
LMNA P02545 2/20 0.46
MEN1 O00255 2/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2C9 P11712 2/20 0.46
AKR1B10 O60218 1/20 0.46
ABCB11 O95342 1/20 0.46
DHFR P00374 1/20 0.46
MPO P05164 1/20 0.46
CYP1A2 P05177 1/20 0.46
CHRM1 P11229 1/20 0.46
AKR1B1 P15121 1/20 0.46
PTGS1 P23219 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL1716527 0.98 ESR1 (0.47) ESR1ESR2ALDH1A1HSD17B10KDM4E
Hydrazine SCHEMBL9506838 0.96 ESR1 (0.46) ESR1ESR2ALDH1A1HSD17B10KDM4E
SCHEMBL2300929 0.88 ALDH1A1 (0.50) ESR1ESR2ALDH1A1HSD17B10KDM4E
SCHEMBL7430270 0.82 MYC (0.49) ALDH1A1HSD17B10KDM4EHPGDKMT2A
SCHEMBL29563004 0.82 MYC (0.52) ALDH1A1HSD17B10KDM4EHPGDKMT2A
SCHEMBL7124951 0.81 TRPA1 (0.48) ESR1ESR2ALDH1A1HSD17B10KDM4E
SCHEMBL29677294 0.81 ALDH1A1 (0.54) ALDH1A1HSD17B10KDM4EHPGDKMT2A
SCHEMBL93382 0.81 ALDH1A1 (0.54) ALDH1A1HSD17B10KDM4EHPGDKMT2A
SCHEMBL9864607 0.81 ESR1 (0.52) ESR1ESR2ALDH1A1HSD17B10KDM4E
SCHEMBL29515031 0.81 KMT2A (0.52) ESR1ESR2ALDH1A1HSD17B10KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 689 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250304541-A1 METHYLENE BLUE HAVING A REDUCED CONTENT OF N-NITROSO-AZURE B IMPURITY AND PROCESS FOR OBTAINING THE SAME Icrom S.R.L. (IT) 2025-10-02 US claimed
CN-119504594-A Dexmedetomidine hydrochloride raw material and injection preparation method 江西赣南海欣药业股份有限公司 2025-02-25 CN claimed
CN-117986232-A Oxime ester photoinitiator, preparation method and application thereof 常州强力电子新材料股份有限公司 2024-05-07 CN claimed
CN-115586282-A Method for quantifying trace silicon hydroxyl in MQ silicon resin 杭州师范大学 2023-01-10 CN claimed
CN-110922313-A Method for continuously producing aromatic ketone 连云港德洋化工有限公司 2020-03-27 CN claimed
CN-109851492-A The synthetic method of 3,5- dimethyl benzoyl chlorides 山东凯盛新材料股份有限公司 2019-06-07 CN claimed
CN-109608400-A A kind of synthetic method of dexmedetomidine hydrochloride 辰欣药业股份有限公司 2019-04-12 CN claimed
CN-109134241-A The industrial process of 3,5- dimethyl benzoyl chloride 山东凯盛新材料股份有限公司 2019-01-04 CN claimed
CN-104693062-B Phenylacetylene derivatives and preparation of the side base with ester group, polymerization and methods for using them 哈尔滨工程大学 2017-10-03 CN claimed
CN-104910039-A Functional phenylacetylene compound and preparation method thereof UNIV HARBIN ENG 2015-09-16 CN claimed
US-20010014759-A1 Free radical chlorination; fluorination with hydrogen fluoride and/or antimony pentafluoride; converting the benzoyl fluoride to chloride by reacting with silicon tetrachloride in lewis acid; chemical intermediates LANXESS DEUTSCHLAND GMBH (DE) 2001-08-16 US claimed
CN-1308050-A Preparation method of 3,5-di (trifluoromethyl) benzoyl chloride and new 3,5-di(triahlo) benzoylate A and 3,5-dimethyl benzoylate A BAYER AG (DE) 2001-08-15 CN claimed
EP-0639559-B1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM & HAAS (US) 1997-10-15 EP claimed
EP-0639559-A1 Preparation of 1,2-diacyl-2-(t-alkyl)hydrazines ROHM AND HAAS COMPANY (US) 1995-02-22 EP claimed
US-5334724-A Preparation of substituted 2-chloropyridines BAYER AKTIENGESELLSCHAFT (DE) 1994-08-02 US claimed
EP-0438691-B1 Process for the preparation of substituted 2-chloropyridines BAYER AG (DE) 1994-02-16 EP claimed
WO-1993014055-A1 PREPARATION OF 2,5-DICHLOROBENZOPHENONES MAXDEM INCORPORATED (US) 1993-07-22 WO claimed
US-5210313-A Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids MAXDEM INCORPORATED (US) 1993-05-11 US claimed
EP-0438691-A1 Process for the preparation of substituted 2-chloropyridines BAYER AG (DE) 1991-07-31 EP claimed
US-4272502-A Process for preparing gaseous hydrogen chloride from dilute aqueous hydrochloric acid CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DE) 1981-06-09 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010014759-A1 Free radical chlorination; fluorination with hydrogen fluoride and/or antimony pentafluoride; converting the benzoyl fluoride to chloride by reacting with silicon tetrachloride in lewis acid; chemical intermediates SCLY, SSB, CLIC4 ESR1 2480/4885ESR2 2026/4885ALDH1A1 3242/4885
US-20250304541-A1 METHYLENE BLUE HAVING A REDUCED CONTENT OF N-NITROSO-AZURE B IMPURITY AND PROCESS FOR OBTAINING THE SAME MMAB, HBB, MB ESR1 3226/4885ESR2 2117/4885ALDH1A1 702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.