Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | VCAM1 | P19320 | 2/20 | 0.46 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.45 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27458114 | 0.88 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AVCAM1RAD51 | |
| SCHEMBL28110970 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AABCG2 | |
| SCHEMBL30129995 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL360009 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL28110425 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AGAAHTT | |
| SCHEMBL29620071 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL4866756 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AGAAHTT | |
| SCHEMBL2810966 | 0.76 | ALDH1A1 (0.63) | ALDH1A1MEN1KMT2AHTT | |
| SCHEMBL27569712 | 0.76 | HPGDS (0.52) | ALDH1A1MEN1KMT2AVCAM1RAD51 | |
| SCHEMBL29642602 | 0.74 | ALDH1A1 (1.00) | ALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4522615-A1 | LRRK2 INHIBITORS | Interline Therapeutics, Inc. (US) | 2025-03-19 | — | — | EP | disclosed |
| WO-2023220238-A1 | LRRK2 INHIBITORS | INTERLINE THERAPEUTICS, INC. (US) | 2023-11-16 | — | — | WO | disclosed |
| CN-111051304-B | Imidazo [4,5-c ] quinoline derivatives as LRRK2 inhibitors | 辉瑞大药厂 | 2022-12-27 | — | — | CN | disclosed |