Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.78 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157775 | 0.92 | P2RX7 (0.82) | P2RX7OPRM1OPRD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3750944 | 0.88 | P2RX7 (1.00) | P2RX7 | |
| SCHEMBL30157798 | 0.85 | HPGD (0.62) | P2RX7ALDH1A1SMN1; SMN2KMT2A | |
| SCHEMBL30158761 | 0.85 | P2RX7 (0.84) | P2RX7OPRM1OPRD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL3664155 | 0.85 | P2RX7 (1.00) | P2RX7OPRM1OPRD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9437343 | 0.80 | ALDH1A1 (0.67) | P2RX7OPRM1OPRD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9687693 | 0.79 | P2RX7 (0.62) | P2RX7OPRM1OPRD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL30924083 | 0.78 | ACKR3 (0.62) | ALDH1A1 | |
| SCHEMBL9688612 | 0.78 | P2RX7 (0.66) | P2RX7OPRM1OPRD1ALDH1A1SMN1; SMN2 | |
| SCHEMBL9437306 | 0.78 | OPRM1 (0.64) | P2RX7OPRM1OPRD1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |