Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157499 | 0.90 | P2RX7 (0.53) | NPC1RAB9AP2RX7KMT2AMEN1 | |
| SCHEMBL30157907 | 0.87 | P2RX7 (0.48) | RAB9AP2RX7KMT2AMEN1HPGD | |
| SCHEMBL30157560 | 0.86 | P2RX7 (0.49) | NPC1RAB9AP2RX7KMT2AMEN1 | |
| SCHEMBL30157719 | 0.86 | ALDH1A1 (0.51) | GAAP2RX7KMT2AMEN1TDP1 | |
| SCHEMBL30158093 | 0.86 | P2RX7 (0.53) | P2RX7KMT2AHPGD | |
| SCHEMBL30157349 | 0.86 | P2RX7 (0.51) | NPC1RAB9AP2RX7KMT2AMEN1 | |
| SCHEMBL30157387 | 0.86 | P2RX7 (0.48) | NPC1RAB9AGAAP2RX7KMT2A | |
| SCHEMBL30157993 | 0.86 | P2RX7 (0.55) | P2RX7KMT2A | |
| SCHEMBL30157572 | 0.85 | P2RX7 (0.50) | NPC1P2RX7KMT2AMEN1TDP1 | |
| SCHEMBL30157597 | 0.85 | P2RX7 (0.52) | NPC1RAB9AP2RX7KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |