Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 3/20 | 0.56 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CCR1 | P32246 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157458 | 0.87 | P2RX7 (0.52) | P2RX7RAB9ANPC1HDAC1HDAC2 | |
| SCHEMBL30157885 | 0.86 | P2RX7 (0.60) | P2RX7ALDH1A1RAB9ANPC1POLB | |
| SCHEMBL30157660 | 0.82 | KMT2A (0.49) | P2RX7ALDH1A1RAB9AHDAC1HDAC2 | |
| SCHEMBL30158065 | 0.81 | SIGMAR1 (0.53) | P2RX7ALDH1A1POLBKMT2A | |
| SCHEMBL30157822 | 0.81 | P2RX7 (0.52) | P2RX7KMT2A | |
| SCHEMBL30157538 | 0.79 | P2RX7 (0.48) | P2RX7RAB9ANPC1HDAC1HDAC2 | |
| SCHEMBL30157596 | 0.78 | P2RX7 (0.48) | P2RX7ALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL30157582 | 0.76 | KMT2A (0.65) | ALDH1A1HDAC1HDAC2SMN1; SMN2KMT2A | |
| SCHEMBL1611778 | 0.75 | P2RX7 (0.60) | P2RX7ALDH1A1POLBSMN1; SMN2KMT2A | |
| SCHEMBL289453 | 0.75 | P2RX7 (0.60) | P2RX7ALDH1A1POLBSMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |