Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30157712 | 0.90 | KMT2A (0.57) | KMT2AALDH1A1GAANPC1HTT | |
| SCHEMBL30158819 | 0.87 | KMT2A (0.43) | TSHRKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL30157904 | 0.84 | P2RX7 (0.44) | TSHRKMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL30157492 | 0.83 | KMT2A (0.44) | TSHRKMT2AMEN1ALDH1A1HDAC1 | |
| SCHEMBL30158549 | 0.83 | KMT2A (0.44) | TSHRKMT2AMEN1ALDH1A1HDAC1 | |
| SCHEMBL30157628 | 0.83 | EPHX2 (0.44) | TSHRKMT2APOLBMEN1HDAC1 | |
| SCHEMBL30157508 | 0.83 | LMNA (0.40) | KMT2AMEN1LMNAALDH1A1HDAC1 | |
| SCHEMBL30157408 | 0.82 | SIGMAR1 (0.51) | TSHRKMT2APOLBLMNAALDH1A1 | |
| SCHEMBL30157737 | 0.82 | EPHX2 (0.56) | KMT2AMEN1ALDH1A1MAPTKDM4E | |
| SCHEMBL30157407 | 0.81 | BRD4 (0.47) | KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |