Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31706028 | 0.87 | ITGB1 (0.47) | HCRTR2POLBTSHRCYP2C19HCRTR1 | |
| SCHEMBL30158549 | 0.86 | KMT2A (0.44) | HCRTR2GAATSHRCYP2D6CYP2C19 | |
| SCHEMBL30158802 | 0.86 | P2RX7 (0.39) | HCRTR2GAAPOLBTSHRALOX15 | |
| SCHEMBL30158532 | 0.86 | KMT2A (0.56) | GAACYP2C19KMT2AHTTMEN1 | |
| SCHEMBL30158611 | 0.85 | ALDH1A1 (0.50) | HCRTR2GAAPOLBTSHRKMT2A | |
| SCHEMBL30158699 | 0.85 | ALDH1A1 (0.50) | HCRTR2GAAPOLBTSHRKMT2A | |
| SCHEMBL31705306 | 0.84 | KMT2A (0.48) | HCRTR2KMT2AMEN1HCRTR1P2RX7 | |
| SCHEMBL30158670 | 0.83 | PTGER2 (0.49) | POLBKMT2AHTTMEN1ALDH1A1 | |
| SCHEMBL30158686 | 0.82 | MDM2 (0.38) | HCRTR2TSHRKMT2AHCRTR1ALDH1A1 | |
| SCHEMBL30158432 | 0.81 | KMT2A (0.43) | KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |