Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GYS1 | P13807 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30158699 | 1.00 | ALDH1A1 (0.50) | ALDH1A1TSHRL3MBTL1SIGMAR1KDM4E | |
| SCHEMBL30157534 | 0.89 | ALDH1A1 (0.41) | ALDH1A1TSHRL3MBTL1SIGMAR1KDM4E | |
| SCHEMBL30158612 | 0.87 | P2RX7 (0.44) | ALDH1A1TSHRL3MBTL1P2RX7PTGER3 | |
| SCHEMBL30158686 | 0.87 | MDM2 (0.38) | ALDH1A1TSHRL3MBTL1GYS1P2RX7 | |
| SCHEMBL30157815 | 0.85 | KMT2A (0.44) | ALDH1A1TSHRL3MBTL1SIGMAR1KDM4E | |
| SCHEMBL30158586 | 0.85 | HCRTR2 (0.49) | ALDH1A1TSHRP2RX7GAAKMT2A | |
| SCHEMBL30157408 | 0.84 | SIGMAR1 (0.51) | ALDH1A1TSHRL3MBTL1SIGMAR1GYS1 | |
| SCHEMBL31705306 | 0.84 | KMT2A (0.48) | SIGMAR1RAB9AP2RX7KMT2AHCRTR1 | |
| SCHEMBL30158802 | 0.83 | P2RX7 (0.39) | TSHRSIGMAR1RAB9AP2RX7GAA | |
| SCHEMBL31706278 | 0.81 | MDM2 (0.51) | ALDH1A1L3MBTL1SIGMAR1KDM4EP2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |