Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MDM2 | Q00987 | 4/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.34 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.34 |
| ▸ | GYS1 | P13807 | 1/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.33 |
| ▸ | GRIN3B | O60391 | 3/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.33 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.33 |
| ▸ | GRIN3A | Q8TCU5 | 3/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30158802 | 0.88 | P2RX7 (0.39) | P2RX7TSHRHCRTR1HCRTR2KMT2A | |
| SCHEMBL30158611 | 0.87 | ALDH1A1 (0.50) | P2RX7ALDH1A1TSHRL3MBTL1HCRTR1 | |
| SCHEMBL30158699 | 0.87 | ALDH1A1 (0.50) | P2RX7ALDH1A1TSHRL3MBTL1HCRTR1 | |
| SCHEMBL24809891 | 0.83 | RIPK1 (0.40) | P2RX7FFAR4 | |
| SCHEMBL31551184 | 0.83 | RIPK1 (0.40) | P2RX7FFAR4 | |
| SCHEMBL30158586 | 0.82 | HCRTR2 (0.49) | P2RX7ALDH1A1TSHRHCRTR1HCRTR2 | |
| SCHEMBL30158612 | 0.82 | P2RX7 (0.44) | P2RX7ALDH1A1TSHRL3MBTL1HCRTR1 | |
| SCHEMBL31705306 | 0.81 | KMT2A (0.48) | P2RX7HCRTR1HCRTR2KMT2A | |
| SCHEMBL30158747 | 0.80 | FFAR4 (0.43) | P2RX7FFAR4 | |
| SCHEMBL31706028 | 0.80 | ITGB1 (0.47) | MDM2P2RX7TSHRHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022268520-A1 | USE OF SUBSTITUTED PYRROLIDINONES OR THEIR SALTS FOR INCREASING STRESS TOLERANCE OF PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-12-29 | — | — | WO | disclosed |