SCHEMBL3015902

SCHEMBL3015902

CN1C(=O)C(Cc2c(F)cccc2C#N)N(C)C(=O)C1Cc1ccc(F)cc1

nearest known ligand 0.45

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 1/20 0.45
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
MDM2 Q00987 2/20 0.35
GLA P06280 1/20 0.35
MAPT P10636 1/20 0.35
LMNA P02545 1/20 0.34
PPARG P37231 1/20 0.33
KCNA5 P22460 1/20 0.33
P2RX7 Q99572 1/20 0.33
KDM4E B2RXH2 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HSD17B10 Q99714 1/20 0.33
AR P10275 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3022057 0.92 CAPN1 (0.43) CAPN1MEN1KMT2AMAPTLMNA
SCHEMBL3021484 0.88 CAPN1 (0.43) CAPN1MDM2PPARGKDM4EALDH1A1
SCHEMBL3031709 0.86 CAPN1 (0.45) CAPN1MEN1KMT2AMDM2GLA
SCHEMBL27797712 0.85 CAPN1 (0.40) CAPN1MEN1KMT2AMDM2GLA
SCHEMBL3025192 0.83 CAPN1 (0.47) CAPN1MEN1KMT2AMDM2GLA
SCHEMBL3017368 0.82 AR (0.33) KCNA5KDM4EALDH1A1AR
SCHEMBL3796902 0.81 KCNA5 (0.32) MEN1KMT2AKCNA5AR
SCHEMBL3024183 0.79 CAPN1 (0.42) CAPN1MDM2MAPTLMNAKDM4E
SCHEMBL3023698 0.79 CAPN1 (0.42) CAPN1MEN1KMT2AMAPTALDH1A1
SCHEMBL3021942 0.77 MEN1 (0.33) MEN1KMT2AKCNA5AR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100190794-A1 Herbicidally Active Composition BASF SE (DE) 2010-07-29 US claimed
EP-2157856-A1 HERBICIDALLY EFFECTIVE COMPOSITION Basf Se (DE) 2010-03-03 EP claimed
WO-2008152074-A1 HERBICIDALLY EFFECTIVE COMPOSITION BASF SE (DE) 2008-12-18 WO claimed
US-20100190794-A1 Herbicidally Active Composition BASF SE (DE) 2010-07-29 US disclosed
EP-2157856-A1 HERBICIDALLY EFFECTIVE COMPOSITION Basf Se (DE) 2010-03-03 EP disclosed
WO-2008152074-A1 HERBICIDALLY EFFECTIVE COMPOSITION BASF SE (DE) 2008-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100190794-A1 Herbicidally Active Composition ECI1, ACLY, SQOR CAPN1 3690/4885MEN1 4521/4885KMT2A 2213/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.