SCHEMBL3025192

SCHEMBL3025192

CN1C(=O)C(Cc2ccccc2C#N)N(C)C(=O)C1Cc1ccc(F)cc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CAPN1 P07384 1/20 0.47
DPP4 P27487 1/20 0.42
TACR1 P25103 2/20 0.41
GLA P06280 1/20 0.38
MAPT P10636 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
LMNA P02545 1/20 0.37
MDM2 Q00987 2/20 0.37
MAPK14 Q16539 1/20 0.35
GRIN1 Q05586 1/20 0.35
GRIN2B Q13224 1/20 0.35
FFAR1 O14842 1/20 0.34
CES2 O00748 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34
PPARG P37231 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3026144 0.90 CAPN1 (0.48) CAPN1DPP4TACR1MAPTMEN1
SCHEMBL3015902 0.83 CAPN1 (0.45) CAPN1GLAMAPTMEN1KMT2A
SCHEMBL3010581 0.81 DPP4 (0.37) DPP4TACR1KMT2AMAPK14GRIN1
SCHEMBL3021484 0.81 CAPN1 (0.43) CAPN1TACR1MDM2GRIN1GRIN2B
SCHEMBL3799444 0.80 TACR1 (0.35) DPP4TACR1MAPK14GRIN1GRIN2B
SCHEMBL27797712 0.78 CAPN1 (0.40) CAPN1GLAMAPTMEN1KMT2A
SCHEMBL3031709 0.78 CAPN1 (0.45) CAPN1GLAMAPTMEN1KMT2A
SCHEMBL27750542 0.78 MAPT (0.46) CAPN1DPP4MAPTMEN1KMT2A
SCHEMBL3022057 0.77 CAPN1 (0.43) CAPN1DPP4TACR1MAPTMEN1
SCHEMBL13799188 0.76 CAPN1 (0.48) CAPN1DPP4TACR1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100190794-A1 Herbicidally Active Composition BASF SE (DE) 2010-07-29 US claimed
CN-101677540-A Herbicidally effective composition EIKE HUPE 2010-03-24 CN claimed
EP-2157856-A1 HERBICIDALLY EFFECTIVE COMPOSITION Basf Se (DE) 2010-03-03 EP claimed
WO-2008152074-A1 HERBICIDALLY EFFECTIVE COMPOSITION BASF SE (DE) 2008-12-18 WO claimed
US-20100190794-A1 Herbicidally Active Composition BASF SE (DE) 2010-07-29 US disclosed
CN-101677540-A Herbicidally effective composition EIKE HUPE 2010-03-24 CN disclosed
EP-2157856-A1 HERBICIDALLY EFFECTIVE COMPOSITION Basf Se (DE) 2010-03-03 EP disclosed
CN-101365687-A Piperazine compounds having herbicidal action BASF SE (DE) 2009-02-11 CN disclosed
WO-2008152074-A1 HERBICIDALLY EFFECTIVE COMPOSITION BASF SE (DE) 2008-12-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100190794-A1 Herbicidally Active Composition ECI1, ACLY, SQOR CAPN1 3690/4885DPP4 1470/4885TACR1 2586/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.