Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1309189 | 0.93 | ALOX15 (0.59) | ALOX15MAPK1SMN1; SMN2HCAR2KMT2A | |
| SCHEMBL3016713 | 0.90 | ALOX15 (0.49) | ALOX15MAPK1SMN1; SMN2HCAR2CACNA1G | |
| SCHEMBL1308602 | 0.84 | L3MBTL1 (0.52) | ALOX15MAPK1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL1309054 | 0.83 | POLB (0.55) | MAPK1SMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL15752071 | 0.83 | GSK3B (0.48) | ALOX15MAPK1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL1309175 | 0.81 | ALDH1A1 (0.58) | MAPK1SMN1; SMN2KMT2AALDH1A1MEN1 | |
| SCHEMBL1308550 | 0.81 | MEN1 (0.54) | SMN1; SMN2KMT2AALDH1A1MEN1LMNA | |
| SCHEMBL15751904 | 0.81 | POLB (0.55) | ALOX15MAPK1SMN1; SMN2KMT2AALDH1A1 | |
| SCHEMBL1308253 | 0.81 | POLB (0.41) | ALOX15MAPK1SMN1; SMN2KMT2ATRPV1 | |
| SCHEMBL1308217 | 0.81 | MEN1 (0.39) | ALOX15MAPK1SMN1; SMN2KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100292283-A1 | NOVEL PHENYL-ACETAMIDE AND PHENYL-PROPIONAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-11-18 | — | — | US | claimed |
| EP-2225214-A1 | NOVEL PHENYL-ACETAMIDE AND PHENYL-PROPIONAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NeuroSearch AS (DK) | 2010-09-08 | — | — | EP | claimed |
| WO-2009068557-A1 | NOVEL PHENYL-ACETAMIDE AND PHENYL-PROPIONAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2009-06-04 | — | — | WO | claimed |
| US-20100292283-A1 | NOVEL PHENYL-ACETAMIDE AND PHENYL-PROPIONAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2010-11-18 | — | — | US | disclosed |
| EP-2225214-A1 | NOVEL PHENYL-ACETAMIDE AND PHENYL-PROPIONAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NeuroSearch AS (DK) | 2010-09-08 | — | — | EP | disclosed |
| WO-2009068557-A1 | NOVEL PHENYL-ACETAMIDE AND PHENYL-PROPIONAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | NEUROSEARCH A/S (DK) | 2009-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100292283-A1 | NOVEL PHENYL-ACETAMIDE AND PHENYL-PROPIONAMIDE DERIVATIVES USEFUL AS POTASSIUM CHANNEL MODULATORS | KCNN2, KCNN1, KCNN3 | ALOX15 3952/4885MAPK1 1196/4885SMN1; SMN2 2202/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.