Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | WDR5 | P61964 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.43 |
| ▸ | KAT7 | O95251 | 1/20 | 0.43 |
| ▸ | KAT6B | Q8WYB5 | 1/20 | 0.43 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25450208 | 1.00 | ALPL (0.51) | ALPLALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL25450154 | 0.86 | SMN1; SMN2 (0.56) | ALPLALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL30161390 | 0.86 | SMN1; SMN2 (0.56) | ALPLALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL30161652 | 0.85 | ALDH1A1 (0.66) | ALPLALDH1A1MAPTSMN1; SMN2CASP1 | |
| SCHEMBL25450202 | 0.85 | ALDH1A1 (0.66) | ALPLALDH1A1MAPTSMN1; SMN2CASP1 | |
| SCHEMBL30161354 | 0.85 | NPC1 (0.62) | ALPLALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL25450199 | 0.85 | SMN1; SMN2 (0.59) | ALPLALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL25450006 | 0.85 | NPC1 (0.62) | ALPLALDH1A1MAPTSMN1; SMN2TSHR | |
| SCHEMBL25450174 | 0.77 | KEAP1 (0.60) | ALDH1A1MAPTSMN1; SMN2TSHRTP53 | |
| SCHEMBL30161175 | 0.77 | KEAP1 (0.60) | ALDH1A1MAPTSMN1; SMN2TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115768750-A | GCN2 modulator compounds | 阿莱斯塔治疗公司 | 2023-03-07 | — | — | CN | disclosed |
| EP-4107146-A1 | GCN2 MODULATOR COMPOUNDS | Alesta Therapeutics BV (NL) | 2022-12-28 | — | — | EP | disclosed |