Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2789335 | 1.00 | CYP19A1 (0.43) | CYP19A1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL21476229 | 0.85 | CYP4F2 (0.53) | HSD17B10CYP4Z1SYKLMNAMAPT | |
| SCHEMBL12303297 | 0.84 | SYK (0.50) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL16797558 | 0.84 | ALDH1A1 (0.47) | CYP19A1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL29919922 | 0.84 | ALDH1A1 (0.47) | CYP19A1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL4420980 | 0.84 | SMN1; SMN2 (0.45) | CYP19A1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL16108961 | 0.83 | LOX (0.53) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL30088474 | 0.83 | LOX (0.53) | SMN1; SMN2NPC1PKMNFKB1RAB9A | |
| SCHEMBL13653554 | 0.83 | CDC7 (0.49) | CYP19A1SMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL191331 | 0.81 | RECQL (0.50) | CYP19A1SMN1; SMN2NPC1PKMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025082316-A1 | OPHTHALMIC FORMATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州必扬医药科技有限公司 | 2025-04-24 | — | — | WO | disclosed |
| US-20230061841-A1 | SHMT INHIBITORS AND USES THEREOF | RAZE THERAPEUTICS, INC. | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230061841-A1 | SHMT INHIBITORS AND USES THEREOF | SHMT1, SHMT2, BHMT | CYP19A1 1469/4885SMN1; SMN2 4027/4885NPC1 2512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.