SCHEMBL30166006

SCHEMBL30166006

COC1=Cc2cc(-c3ccc(OC)c(OC)c3)cc3cccc(c23)C1=O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.45
ADORA3 P0DMS8 2/20 0.42
ADORA2A P29274 1/20 0.42
KDM4E B2RXH2 3/20 0.40
MAPT P10636 3/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
TSHR P16473 2/20 0.40
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
LMNA P02545 1/20 0.40
PKM P14618 1/20 0.40
ALOX12 P18054 1/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
MAOA P21397 1/20 0.40
IDO1 P14902 1/20 0.39
CDC25A P30304 1/20 0.39
CDC25B P30305 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28929060 1.00 L3MBTL1 (0.45) L3MBTL1ADORA3ADORA2AKDM4EMAPT
SCHEMBL28929033 0.90 MAOA (0.46) L3MBTL1ADORA3ADORA2AKDM4EMAPT
SCHEMBL30166015 0.90 MAOA (0.46) L3MBTL1ADORA3ADORA2AKDM4EMAPT
SCHEMBL28928992 0.89 NPC1 (0.45) ADORA3ADORA2AKDM4EMAPTALDH1A1
SCHEMBL30165992 0.86 L3MBTL1 (0.44) L3MBTL1ADORA3ADORA2AKDM4EMAPT
SCHEMBL28929049 0.86 L3MBTL1 (0.44) L3MBTL1ADORA3ADORA2AKDM4EMAPT
SCHEMBL28929477 0.85 GAPDH (0.45) L3MBTL1ADORA3KDM4EMAPTTSHR
SCHEMBL28928975 0.84 CDC25A (0.46) KDM4EMAPTALDH1A1HPGDMEN1
SCHEMBL28929042 0.81 L3MBTL1 (0.46) L3MBTL1ADORA3ADORA2AKDM4EMAPT
SCHEMBL30166013 0.81 L3MBTL1 (0.46) L3MBTL1ADORA3ADORA2AKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115583876-B Phenyl naphthacene ketone compound and preparation method and application thereof 深圳技术大学 2023-12-19 CN disclosed
CN-115583876-A Phenyl-naphthalenepophenone compounds, preparation method and application thereof 深圳技术大学 2023-01-10 CN disclosed