Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | CDC25A | P30304 | 1/20 | 0.40 |
| ▸ | CDC25B | P30305 | 1/20 | 0.40 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28962245 | 0.90 | MAOA (0.46) | NPC1SMN1; SMN2ALOX5ADORA3ADORA2A | |
| SCHEMBL28929060 | 0.89 | L3MBTL1 (0.45) | NPC1SMN1; SMN2ADORA3ADORA2AMAPT | |
| SCHEMBL30166006 | 0.89 | L3MBTL1 (0.45) | NPC1SMN1; SMN2ADORA3ADORA2AMAPT | |
| SCHEMBL28929057 | 0.86 | ALOX5 (0.49) | NPC1SMN1; SMN2ALOX5ADORA3ADORA2A | |
| SCHEMBL28928975 | 0.85 | CDC25A (0.46) | NPC1SMN1; SMN2ALOX5MAPTMAOA | |
| SCHEMBL28929477 | 0.83 | GAPDH (0.45) | NPC1SMN1; SMN2ADORA3MAPTMAOA | |
| SCHEMBL28929016 | 0.81 | CYP1A2 (0.49) | NPC1SMN1; SMN2ADORA3MAPTMAOA | |
| SCHEMBL30165985 | 0.81 | CYP1A2 (0.49) | NPC1SMN1; SMN2ADORA3MAPTMAOA | |
| SCHEMBL28929039 | 0.81 | ADORA3 (0.47) | NPC1SMN1; SMN2ALOX5ADORA3ADORA2A | |
| SCHEMBL28962247 | 0.81 | NPC1 (0.46) | NPC1SMN1; SMN2ALOX5ADORA3ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583876-B | Phenyl naphthacene ketone compound and preparation method and application thereof | 深圳技术大学 | 2023-12-19 | — | — | CN | disclosed |
| CN-115583876-A | Phenyl-naphthalenepophenone compounds, preparation method and application thereof | 深圳技术大学 | 2023-01-10 | — | — | CN | disclosed |