Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CFB | P00751 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | VCP | P55072 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 2/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Abafungin SCHEMBL29517947 | 1.00 | MEN1 (0.42) | MEN1KMT2AATMMAPTALDH1A1 | |
| Abafungin SCHEMBL10455902 | 0.99 | MEN1 (0.41) | MEN1KMT2AATMMAPTALDH1A1 | |
| Abafungin SCHEMBL28095068 | 0.94 | MEN1 (0.38) | MEN1KMT2AATMMAPTALDH1A1 | |
| Abafungin SCHEMBL28223793 | 0.93 | MEN1 (0.37) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL8310278 | 0.84 | VCP (0.44) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL24996622 | 0.80 | PTGS2 (0.38) | MEN1KMT2AMAPTALDH1A1TDP1 | |
| Abafungin SCHEMBL301668 | 0.75 | MAPT (0.39) | MEN1KMT2AATMMAPTALDH1A1 | |
| SCHEMBL10455731 | 0.74 | ALOX5 (0.44) | MEN1KMT2AMAPTALDH1A1PTGS2 | |
| SCHEMBL3605029 | 0.73 | ATP4A (0.45) | MEN1KMT2AATMMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL10455564 | 0.73 | CFB (0.44) | MEN1KMT2AATMMAPTCFB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 3757 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4255391-B1 | LUMINOL FOR USE IN THE TREATMENT OF SEQUELAE OF A SARS-COV-2 INFECTION | METRIOPHARM AG (CH) | 2026-05-06 | — | — | EP | claimed |
| US-20260102419-A1 | USE OF COMPOUNDS IN THE TREATMENT OF FUNGAL INFECTIONS | BASILEA PHARMACEUTICA INTERNATIONAL AG, ALLSCHWIL (CH) | 2026-04-16 | — | — | US | claimed |
| EP-4719384-A2 | COMPOUNDS WITH ANTIFUNGAL PROPERTIES | Trustees of Dartmouth College (US) | 2026-04-08 | — | — | EP | claimed |
| EP-4676500-A2 | MICROBIAL CONSORTIA | Kanvas Biosciences, Inc (US) | 2026-01-14 | — | — | EP | claimed |
| US-20250268998-A1 | METHODS OF TREATMENT FOR CANDIDA AURIS INFECTIONS | LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER | 2025-08-28 | — | — | US | claimed |
| US-12324830-B2 | Methods of treatment for Candida auris infections | LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER | 2025-06-10 | — | — | US | claimed |
| US-12280032-B2 | Methods and compositions for increasing the potency of antifungal agents | PACIFIC NORTHWEST RESEARCH INSTITUTE (US) | 2025-04-22 | — | — | US | claimed |
| WO-2025080590-A1 | CO-CRYSTALLIZATION OF ACTIVES WITH SACCHARIDE-BASED MOLECULAR FRAMEWORKS | SCIENTIFIC HORIZONS CONSULTING LLC (US) | 2025-04-17 | — | — | WO | claimed |
| CN-114746415-B | Polymorphs of triazole antifungal compound PC945 | 普尔莫赛德有限公司 | 2025-04-11 | — | — | CN | claimed |
| US-12269814-B2 | Process for preparing a compound useful to treat mycoses | PULMOCIDE LIMITED (GB) | 2025-04-08 | — | — | US | claimed |
| WO-2009053741-A2 | NOVEL FORMULATION | YORK PHARMA PLC (GB) | 2009-04-30 | — | — | WO | claimed |
| CN-101396363-A | Composite antibacterial drugs composition containing abafungin | CHONGQING PHARMACEUTICAL RESEA (CN) | 2009-04-01 | — | — | CN | claimed |
| CN-101372486-A | Preparation of abafungin and analogues thereof | CHENGDU QIAOFENG TECHNOLOGICAL (CN) | 2009-02-25 | — | — | CN | claimed |
| EP-1682146-B1 | ANTIMYCOTIC NAIL POLISH FORMULATIONS COMPRISING SUBSTITUTED 2-AMINOTHIAZOLES AS AN ACTIVE SUBSTANCE | YORK PHARMA PLC (GB) | 2008-01-09 | — | — | EP | claimed |
| CN-1969874-A | Externally applied pharmaceutical composition of abafungin | CHONGQING PHARM RES INST CO (CN) | 2007-05-30 | — | — | CN | claimed |
| US-20070059261-A1 | Antimycotic nail polish formulations comprising substituted 2-aminothiazoles as an active substance | ULURU INC. | 2007-03-15 | — | — | US | claimed |
| EP-1682146-A1 | ANTIMYCOTIC NAIL POLISH FORMULATIONS COMPRISING SUBSTITUTED 2-AMINOTHIAZOLES AS AN ACTIVE SUBSTANCE | York Pharma PLC (GB) | 2006-07-26 | — | — | EP | claimed |
| WO-2005034956-A1 | ANTIMYCOTIC NAIL POLISH FORMULATIONS COMPRISING SUBSTITUTED 2-AMINOTHIAZOLES AS AN ACTIVE SUBSTANCE | YORK PHARMA PLC (GB) | 2005-04-21 | — | — | WO | claimed |
| EP-0718296-B1 | Thermodynamically stable form of N-[4-[2-(2,4-dimethyl phenoxy)-phenyl]-2-thiazolyl] -1,4,5,6-tetrahydro-2-pyrimidinamine (DTTP) | BAYER AG (DE) | 1999-05-19 | — | — | EP | claimed |
| EP-0718296-A1 | Thermodynamically stable form of N- 4- 2-(2,4-dimethyl phenoxy)-phenyl -2-thiazolyl -1,4,5,6-tetrahydro-2-pyrimidine (DTTP) | BAYER AG (DE) | 1996-06-26 | — | — | EP | claimed |