Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | NPY1R | P25929 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30168030 | 0.84 | MAPT (0.43) | MAPTMEN1KMT2AMGLLALDH1A1 | |
| SCHEMBL28922137 | 0.84 | CYP19A1 (0.40) | MEN1KMT2AMGLLALDH1A1SMN1; SMN2 | |
| SCHEMBL30168036 | 0.82 | ALDH1A1 (0.40) | MAPTMEN1KMT2ABACE1BACE2 | |
| SCHEMBL28922113 | 0.75 | MEN1 (0.45) | MAPTMEN1KMT2AMGLLSIGMAR1 | |
| SCHEMBL11079440 | 0.75 | CYP19A1 (0.55) | MAPTMEN1KMT2ABACE1BACE2 | |
| SCHEMBL28922117 | 0.75 | ALDH1A1 (0.43) | MAPTMEN1KMT2AKDM1AALDH1A1 | |
| SCHEMBL28922120 | 0.75 | CNR1 (0.45) | MAPTMEN1KMT2AKDM1AMAPK1 | |
| SCHEMBL11463156 | 0.70 | CYP19A1 (0.48) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL11075149 | 0.70 | CYP19A1 (0.50) | MEN1KMT2ABACE1KDM1ACRHBP | |
| SCHEMBL30168035 | 0.67 | ELANE (0.42) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115536573-B | Method for synthesizing azabicyclo [3.1.0] hexane-2-ketone compound | 河南师范大学 | 2024-01-30 | — | — | CN | disclosed |
| CN-115536573-A | Method for synthesizing azabicyclo [3.1.0] hexane-2-ketone compound | 河南师范大学 | 2022-12-30 | — | — | CN | disclosed |