Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | STS | P08842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30168195 | 0.85 | CYP1A2 (0.44) | MAPTALDH1A1LMNAGPR119KMT2A | |
| SCHEMBL1865727 | 0.84 | ALDH1A1 (0.62) | MAPTALDH1A1LMNAGPR119PTPN2 | |
| SCHEMBL4465377 | 0.81 | ALDH1A1 (0.54) | MAPTALDH1A1LMNAGPR119 | |
| SCHEMBL31202940 | 0.81 | FAAH (0.45) | MAPTALDH1A1LMNA | |
| SCHEMBL31203212 | 0.81 | LMNA (0.53) | MAPTALDH1A1LMNAGPR119KDM4E | |
| SCHEMBL31203062 | 0.81 | ALDH1A1 (0.60) | MAPTALDH1A1LMNAKMT2A | |
| SCHEMBL21752546 | 0.80 | GPR119 (0.54) | ALDH1A1GPR119KDM4EPTPN2PTPN1 | |
| SCHEMBL5970392 | 0.79 | MAPT (0.53) | MAPTALDH1A1LMNAGPR119KDM4E | |
| SCHEMBL1810972 | 0.79 | ALDH1A1 (0.70) | MAPTALDH1A1LMNATHRBKMT2A | |
| SCHEMBL29803658 | 0.79 | ALDH1A1 (0.70) | MAPTALDH1A1LMNATHRBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115667264-A | Novel imidazo-pyrazine derivatives | 豪夫迈·罗氏有限公司 | 2023-01-31 | — | — | CN | disclosed |