Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.41 |
| ▸ | PRKCB | P05771 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 1/20 | 0.41 |
| ▸ | PRKCH | P24723 | 1/20 | 0.41 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.41 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.41 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.41 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.41 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.38 |
| ▸ | HTR3B | O95264 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19869853 | 0.89 | DHODH (0.44) | HSD17B10KDM4EALDH1A1HPGDGRM4 | |
| SCHEMBL7237013 | 0.84 | GAA (0.46) | TSHRHSD17B10KDM4EALDH1A1GRM4 | |
| SCHEMBL14912155 | 0.81 | DHODH (0.40) | MTORKDM4EACHEDHODHKDM4C | |
| SCHEMBL30169524 | 0.80 | SLC6A4 (0.46) | HTR6PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL30588460 | 0.77 | DRD2 (0.55) | HTR6PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL1239171 | 0.77 | DRD2 (0.55) | HTR6PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL30169395 | 0.77 | LMNA (0.40) | HTR6P2RX7HTR1ALMNAKDM4C | |
| SCHEMBL7436441 | 0.76 | HTR3A (0.50) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8890709 | 0.76 | ALDH1A1 (0.41) | HTR6PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL1239782 | 0.76 | DRD2 (0.54) | HTR6PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118239959-A | Cyclopropane TLR7 and 8 inhibitor and preparation method and application thereof | 上海深势唯思科技有限责任公司 | 2024-06-25 | — | — | CN | disclosed |
| CN-115551593-A | Compounds and methods for modulating splicing | 雷密克斯医疗公司 | 2022-12-30 | — | — | CN | disclosed |