Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | DHODH | Q02127 | 2/20 | 0.36 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.34 |
| ▸ | KDR | P35968 | 2/20 | 0.34 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30170714 | 0.81 | ELANE (0.34) | ELANETRPV1PDGFRBPDGFRADHODH | |
| SCHEMBL30170681 | 0.80 | DHODH (0.42) | ELANEPDGFRBPDGFRADHODHEPHA2 | |
| SCHEMBL30170771 | 0.80 | ELANE (0.41) | ELANEPDGFRBPDGFRADHODHEPHA2 | |
| SCHEMBL30170868 | 0.80 | ALOX5 (0.38) | ELANETRPV1PDGFRBPDGFRAEPHA2 | |
| SCHEMBL30170824 | 0.80 | SOS1 (0.35) | ELANETRPV1PDGFRBPDGFRAEPHA2 | |
| SCHEMBL20982537 | 0.64 | HTR2A (0.52) | — | |
| SCHEMBL31172781 | 0.64 | MAPT (0.45) | PKMKDM4E | |
| SCHEMBL24791336 | 0.62 | AXL (0.37) | ELANEKDREGFR | |
| SCHEMBL23094469 | 0.62 | KMT2A (0.60) | — | |
| SCHEMBL8184228 | 0.62 | MAOB (0.60) | PDGFRBPDGFRAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022262691-A1 | HETEROCYCLIC COMPOUNDS AS SOS1 INHIBITORS | BEIJING INNOCARE PHARMA TECH CO., LTD. (CN) | 2022-12-22 | — | — | WO | disclosed |