Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | RAB9A | P51151 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 3/20 | 0.32 |
| ▸ | FEN1 | P39748 | 3/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.31 |
| ▸ | SCN4A | P35499 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26453175 | 0.87 | KMT2A (0.45) | KEAP1CYP19A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL1441485 | 0.86 | DGAT1 (0.36) | KEAP1CYP19A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL30944234 | 0.86 | SCN4A (0.46) | CYP19A1SMN1; SMN2MAPTRAB9ANPC1 | |
| SCHEMBL29445621 | 0.83 | CYP19A1 (0.34) | KEAP1CYP19A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL23205956 | 0.82 | ALOX5AP (0.39) | KEAP1SMN1; SMN2MAPTNPC1KMT2A | |
| SCHEMBL401354 | 0.80 | ALDH1A1 (0.39) | NPC1L3MBTL1KMT2AMEN1ALDH1A1 | |
| SCHEMBL3024392 | 0.80 | SCN4A (0.44) | SMN1; SMN2MAPTRAB9ANPC1LMNA | |
| SCHEMBL1366764 | 0.80 | DGAT1 (0.33) | CYP19A1SMN1; SMN2MAPTNPC1L3MBTL1 | |
| SCHEMBL1441484 | 0.78 | LIPG (0.40) | DGAT1 | |
| SCHEMBL1442642 | 0.76 | LPL (0.31) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | PALAU PHARMA, S.A. (ES) | 2010-08-12 | — | — | US | disclosed |
| CN-101679440-A | Pyrrolopyrimidine derivatives as jak3 inhibitors | PALAU PHARMA SA | 2010-03-24 | — | — | CN | disclosed |
| EP-2118105-A1 | PURINE DERIVATIVES | Palau Pharma, S.A. (ES) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008090181-A1 | PURINE DERIVATIVES | PALAU PHARMA, S. A. (ES) | 2008-07-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204187-A1 | Purine Derivatives | JAK3, JAK1, JAK2 | KEAP1 3853/4885CYP19A1 4012/4885SMN1; SMN2 3941/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.