Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CDC7 | O00311 | 3/20 | 0.39 |
| ▸ | PIK3R2 | O00459 | 4/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.36 |
| ▸ | MYC | P01106 | 3/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NNMT | P40261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25528985 | 0.88 | MYC (0.42) | TDP1MYCDHODHNOTUM | |
| SCHEMBL30174168 | 0.77 | TDP1 (0.44) | SIRT3TDP1CDC7MYCCDK9 | |
| SCHEMBL30174246 | 0.76 | MKNK1 (0.47) | SIRT3TDP1MKNK1MKNK2MYC | |
| SCHEMBL30174233 | 0.73 | TYK2 (0.40) | SIRT3TDP1RPS6KB1KDM4E | |
| SCHEMBL29812474 | 0.73 | MYC (0.43) | MYCKDM4EHTT | |
| SCHEMBL28288439 | 0.72 | L3MBTL1 (0.50) | TDP1MYCNOTUMKDM4E | |
| Hydrochloric Acid SCHEMBL30174221 | 0.71 | NNMT (0.35) | PIK3R2MYCTGFBR1NNMT | |
| SCHEMBL30174222 | 0.71 | PDE4B (0.38) | TDP1PIK3R2MYC | |
| SCHEMBL30174184 | 0.71 | AGBL2 (0.38) | SIRT3TDP1MKNK1MKNK2MYC | |
| SCHEMBL30298673 | 0.69 | TDP1 (0.55) | SIRT3TDP1CDC7MKNK1MKNK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |