Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.55 |
| ▸ | CDC7 | O00311 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KDM6B | O15054 | 1/20 | 0.47 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | F7 | P08709 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.44 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2618803 | 1.00 | TDP1 (0.55) | TDP1SIRT3CDC7KDM4EALDH1A1 | |
| SCHEMBL1135627 | 0.83 | SIRT3 (0.60) | TDP1SIRT3CDC7KDM4EALDH1A1 | |
| SCHEMBL30475729 | 0.81 | KDM4C (0.42) | TDP1SIRT3CDC7KDM4EALDH1A1 | |
| SCHEMBL29578794 | 0.81 | KDM4C (0.59) | TDP1KDM4EALDH1A1KDM4CMEN1 | |
| SCHEMBL82604 | 0.81 | KDM4C (0.59) | TDP1KDM4EALDH1A1KDM4CMEN1 | |
| SCHEMBL1330970 | 0.80 | TDP1 (0.67) | TDP1SIRT3CDC7KDM4EALDH1A1 | |
| SCHEMBL1687197 | 0.80 | TDP1 (0.67) | TDP1SIRT3CDC7KDM4EALDH1A1 | |
| SCHEMBL25201864 | 0.79 | KDM4C (0.42) | TDP1SIRT3CDC7KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL1027857 | 0.79 | KDM4C (0.57) | TDP1KDM4EALDH1A1KDM4CMEN1 | |
| SCHEMBL724581 | 0.79 | ALDH1A1 (0.52) | TDP1SIRT3CDC7KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12240862-B2 | Inhibitors of peptidylarginine deiminases | GILEAD SCIENCES, INC. (US) | 2025-03-04 | — | — | US | disclosed |
| CN-117247348-B | Preparation method of 3-fluoro-4-aminopyridine | 科莱博(江苏)科技股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-115915941-A | Pyridine (thio) amides as fungicidal compounds | 拜耳公司 | 2023-04-04 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12240862-B2 | Inhibitors of peptidylarginine deiminases | PADI4, PADI2, PADI1 | TDP1 199/4885SIRT3 1671/4885CDC7 946/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.