Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.37 |
| ▸ | CASR | P41180 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MPI | P34949 | 1/20 | 0.36 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174203 | 0.80 | ERCC1 (0.46) | ALDH1A1NPC1MAPTHSD17B10MEN1 | |
| SCHEMBL30174189 | 0.79 | HPGDS (0.34) | NPC1DAOKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL30174299 | 0.77 | KDM4E (0.36) | ALDH1A1KMT2AKDM4ECYP2C9SMN1; SMN2 | |
| SCHEMBL29868008 | 0.76 | POLB (0.42) | ALDH1A1NPC1MAPTHSD17B10MEN1 | |
| SCHEMBL30174266 | 0.75 | KDM4E (0.58) | ALDH1A1MAPTHSD17B10MEN1KMT2A | |
| SCHEMBL30174207 | 0.75 | KMT2A (0.40) | ALDH1A1NPC1MAPTGFERHSD17B10 | |
| SCHEMBL30174195 | 0.74 | EEF2K (0.41) | NPC1KMT2AKDM4EPOLBALOX5 | |
| SCHEMBL29812778 | 0.73 | KDM4E (0.41) | ALDH1A1NPC1HSD17B10MEN1KMT2A | |
| SCHEMBL30174217 | 0.72 | ALDH1A1 (0.40) | ALDH1A1NPC1MAPTHSD17B10MEN1 | |
| SCHEMBL29868100 | 0.70 | POLB (0.34) | ALDH1A1NPC1HSD17B10MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |