Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | UBE2I | P63279 | 1/20 | 0.35 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.35 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | NNMT | P40261 | 3/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.33 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.33 |
| ▸ | ATF1 | P18846 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28966254 | 0.80 | NEK2 (0.43) | KDM4EALDH1A1HPGDSYK | |
| SCHEMBL30174243 | 0.79 | CHEK1 (0.39) | KDM4EKMT2ASIRT3TDP1NNMT | |
| SCHEMBL30174264 | 0.77 | NNMT (0.39) | KDM4EKMT2ASYKNNMTHPGDS | |
| SCHEMBL30174259 | 0.77 | ALDH1A1 (0.38) | KDM4EKMT2AALDH1A1SMN1; SMN2CYP2C9 | |
| SCHEMBL30174194 | 0.75 | CHEK2 (0.45) | KDM4EALDH1A1 | |
| SCHEMBL29812284 | 0.75 | LMNA (0.44) | KMT2ALMNAJAK2TDP1MAP4K4 | |
| SCHEMBL30174207 | 0.75 | KMT2A (0.40) | KDM4EKMT2AALDH1A1HPGDIKBKE | |
| SCHEMBL30174265 | 0.74 | CYP2A6 (0.43) | KMT2AALDH1A1HPGDSIRT3TDP1 | |
| Hydrochloric Acid SCHEMBL29812079 | 0.73 | LMNA (0.44) | KMT2ALMNAJAK2TDP1MAP4K4 | |
| SCHEMBL30174294 | 0.72 | CHEK2 (0.40) | KMT2AALDH1A1SYKSIRT3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |