Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MPI | P34949 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.33 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.33 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30174200 | 0.79 | KDM4E (0.51) | ALDH1A1KDM4EERN1HSD17B10MAPT | |
| SCHEMBL30174261 | 0.78 | HPGDS (0.36) | KMT2AALDH1A1KDM4EHPGDSHSD17B10 | |
| SCHEMBL30174259 | 0.75 | ALDH1A1 (0.38) | KMT2AMEN1ALDH1A1MPISMN1; SMN2 | |
| SCHEMBL30174299 | 0.75 | KDM4E (0.36) | KMT2AALDH1A1NNMTSMN1; SMN2KDM4E | |
| SCHEMBL30174277 | 0.74 | CHEK2 (0.46) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30174327 | 0.74 | CYP2A6 (0.44) | NPC1HPGDSRAB9AALOX5CCNE2 | |
| SCHEMBL29812074 | 0.73 | SQOR (0.43) | TBK1MAPK1MKNK1MKNK2LIMK1 | |
| SCHEMBL30174231 | 0.72 | CYP3A4 (0.50) | MKNK1MKNK2 | |
| SCHEMBL30174280 | 0.72 | IKBKB (0.43) | KMT2AMEN1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL24800447 | 0.68 | BCAT2 (0.50) | KMT2AMEN1ALDH1A1MPIKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |