Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30466593 | 0.81 | PDGFRB (0.61) | PDGFRBPDGFRAALDH1A1KMT2ANPC1 | |
| SCHEMBL16654428 | 0.77 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2APOLBCASP1 | |
| SCHEMBL27527224 | 0.76 | ALDH1A1 (0.47) | PDGFRBPDGFRAALDH1A1MEN1KMT2A | |
| SCHEMBL9377141 | 0.76 | IDH1 (0.43) | PDGFRBPDGFRAALDH1A1MEN1KMT2A | |
| SCHEMBL30745056 | 0.74 | ALOX15 (0.52) | PDGFRBPDGFRAALDH1A1MEN1KMT2A | |
| SCHEMBL28065783 | 0.73 | TDP1 (0.46) | ALDH1A1MEN1KMT2APOLBCASP1 | |
| SCHEMBL22045250 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MEN1KMT2APOLBCASP1 | |
| SCHEMBL24249193 | 0.72 | ALDH1A1 (0.44) | PDGFRBPDGFRAALDH1A1MEN1KMT2A | |
| SCHEMBL25065371 | 0.72 | ALDH1A1 (0.41) | PDGFRBPDGFRAALDH1A1MEN1KMT2A | |
| SCHEMBL20216792 | 0.72 | PDGFRB (0.74) | PDGFRBPDGFRAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605478-A | Compounds and methods of use | 埃克塞里艾克西斯公司（US） | 2023-01-13 | — | — | CN | disclosed |