Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.52 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.52 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.52 |
| ▸ | CSNK2A3 | Q8NEV1 | 2/20 | 0.52 |
| ▸ | RARB | P10826 | 10/20 | 0.49 |
| ▸ | RARG | P13631 | 9/20 | 0.49 |
| ▸ | RARA | P10276 | 7/20 | 0.49 |
| ▸ | RXRA | P19793 | 6/20 | 0.49 |
| ▸ | RXRB | P28702 | 2/20 | 0.49 |
| ▸ | RXRG | P48443 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9836023 | 0.87 | MAPT (0.52) | CSNK2A2CSNK2BCSNK2A1KDM4EMAPT | |
| SCHEMBL18287649 | 0.83 | RXRA (0.53) | RARBRARGRARARXRARXRB | |
| SCHEMBL18287650 | 0.83 | RXRA (0.53) | RARBRARGRARARXRARXRB | |
| SCHEMBL25229668 | 0.80 | CSNK2A2 (0.61) | CSNK2A2CSNK2BCSNK2A1CSNK2A3KDM4E | |
| SCHEMBL8553327 | 0.79 | TNKS (0.57) | RARBRARGRARARXRARXRB | |
| SCHEMBL28424508 | 0.79 | MAPT (0.64) | CSNK2A2CSNK2BCSNK2A1CSNK2A3KDM4E | |
| SCHEMBL30175553 | 0.77 | MAPT (0.62) | CSNK2A2CSNK2BCSNK2A1CSNK2A3KDM4E | |
| SCHEMBL17940164 | 0.77 | KDM4E (0.56) | CSNK2A2CSNK2BCSNK2A1CSNK2A3KDM4E | |
| SCHEMBL10887195 | 0.74 | MEN1 (0.58) | CSNK2A2CSNK2BCSNK2A1CSNK2A3KDM4E | |
| SCHEMBL6176954 | 0.72 | KDM4E (0.68) | KDM4EMAPTMEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0619116-A2 | Use of synthetic retinoids for osteopathy | HOECHST JAPAN LIMITED (JP) | 1994-10-12 | — | — | EP | claimed |
| EP-0237986-B1 | FLAVONE CARBOXYLIC ACID DERIVATIVES | Shudo, Koichi, Prof. Dr. (JP) | 1991-10-02 | — | — | EP | claimed |
| US-4831052-A | DIFFERENTIATION-INDUCING AGENT FOR CERTAIN MALIONANT CELLS | SHIONOGI & CO., LTD. (JP) | 1989-05-16 | — | — | US | claimed |
| EP-0237986-A2 | Flavone carboxylic acid derivatives | Shudo, Koichi, Prof. Dr. (JP) | 1987-09-23 | — | — | EP | claimed |
| US-5767146-A | Anti-osteopathic composition | HOECHST JAPAN LIMITED (JP) | 1998-06-16 | — | — | US | disclosed |
| US-5716995-A | TREATING OR PREVENTING BONE DISEASES BY ADMINISTERING PHENOLIC, HETERO- OR NAPHTHYL- DERIVATIVES OF 1-HYDROXY-3-OXO-1-PROPENYL BENZOIC ACID TO PROMOTE OSTEOGENESIS | HOECHST JAPAN LIMITED (JP) | 1998-02-10 | — | — | US | disclosed |
| US-5703128-A | TREATING OSTEOPOROSIS, BONE FRACTURES | HOECHST JAPAN LIMITED (JP) | 1997-12-30 | — | — | US | disclosed |
| US-5525618-A | ENHANCING OSTEOGENESIS, PREVENTING OSTEOPOROSIS | HOECHST JAPAN LIMITED (JP) | 1996-06-11 | — | — | US | disclosed |
| EP-0619116-A2 | Use of synthetic retinoids for osteopathy | HOECHST JAPAN LIMITED (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-4925979-A | INTERMEDIATES FOR ANTILEUKEMIA AGENTS, CELL DIFFERENTIATION | SHIONOGI & CO., LTD. (JP) | 1990-05-15 | — | — | US | disclosed |
| US-4831052-A | DIFFERENTIATION-INDUCING AGENT FOR CERTAIN MALIONANT CELLS | SHIONOGI & CO., LTD. (JP) | 1989-05-16 | — | — | US | disclosed |
| EP-0237986-A2 | Flavone carboxylic acid derivatives | Shudo, Koichi, Prof. Dr. (JP) | 1987-09-23 | — | — | EP | disclosed |