Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRS3 | P32247 | 15/20 | 0.50 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6885145 | 0.79 | NPC1 (0.42) | NPC1RAB9A | |
| SCHEMBL21050082 | 0.78 | NPC1 (0.55) | BRS3LTB4R2NPC1GAARAB9A | |
| SCHEMBL29743599 | 0.78 | NPC1 (0.55) | BRS3LTB4R2NPC1GAARAB9A | |
| SCHEMBL30240830 | 0.74 | DHODH (0.58) | BRS3NPC1GAARAB9AKMT2A | |
| SCHEMBL28675025 | 0.74 | GAA (0.54) | BRS3NPC1GAARAB9AKMT2A | |
| SCHEMBL30292805 | 0.74 | HNF4A (0.63) | LTB4R2NPC1RAB9AKMT2A | |
| SCHEMBL18759613 | 0.74 | HNF4A (0.63) | LTB4R2NPC1RAB9AKMT2A | |
| SCHEMBL1874313 | 0.74 | PRKAG1 (0.53) | BRS3NPC1GAARAB9AKMT2A | |
| SCHEMBL31143095 | 0.74 | PIM1 (0.40) | NPC1RAB9A | |
| SCHEMBL17436209 | 0.72 | ALDH1A1 (0.47) | BRS3NPC1GAARAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12023319-B2 | Carboxylic acid aromatic amides | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2024-07-02 | — | — | US | disclosed |
| US-20230043209-A1 | CARBOXYLIC ACID AROMATIC AMIDES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2023-02-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12023319-B2 | Carboxylic acid aromatic amides | DDC, PAH, NAT1 | BRS3 3116/4885LTB4R2 3279/4885NPC1 1233/4885 |
| US-20230043209-A1 | CARBOXYLIC ACID AROMATIC AMIDES | DDC, PAH, NAT1 | BRS3 3116/4885LTB4R2 3279/4885NPC1 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.