SCHEMBL301808

SCHEMBL301808

Clc1cccc(OC(Cl)(Cl)Cl)c1Cl

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.41
RHEB Q15382 1/20 0.41
TSHR P16473 4/20 0.39
KDM4E B2RXH2 2/20 0.39
CYP1A2 P05177 3/20 0.39
CYP3A4 P08684 2/20 0.39
CYP2D6 P10635 2/20 0.39
TP53 P04637 1/20 0.39
CYP2C19 P33261 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
PNMT P11086 2/20 0.37
IDO1 P14902 2/20 0.36
MRGPRX4 Q96LA9 1/20 0.36
CYP2A6 P11509 1/20 0.35
SLC6A2 P23975 2/20 0.34
SLC6A4 P31645 2/20 0.34
SLC6A3 Q01959 2/20 0.34
HTR1A P08908 1/20 0.34
KCNH2 Q12809 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24252065 0.82 ALDH1A1 (0.41) ALDH1A1RHEBTSHRKDM4ECYP1A2
SCHEMBL914798 0.81 LMNA (0.43) ALDH1A1TSHRTDP1SMN1; SMN2SLC6A2
SCHEMBL28003345 0.81 LMNA (0.43) ALDH1A1TSHRTDP1SMN1; SMN2SLC6A2
SCHEMBL8653715 0.80 GRIA1 (0.48) ALDH1A1RHEBTSHRKDM4ECYP1A2
SCHEMBL6298485 0.78 TSHR (0.37) ALDH1A1TSHRKDM4ECYP1A2CYP3A4
SCHEMBL15473230 0.78 KDM4E (0.38) ALDH1A1RHEBTSHRKDM4ECYP1A2
SCHEMBL18071645 0.77 KDM4E (0.37) ALDH1A1RHEBTSHRKDM4ECYP1A2
SCHEMBL12958135 0.77 KDM4E (0.37) ALDH1A1RHEBTSHRKDM4ECYP1A2
SCHEMBL11766505 0.75 PNMT (0.48) ALDH1A1RHEBTSHRKDM4ECYP1A2
SCHEMBL6325195 0.75 RHEB (0.60) ALDH1A1RHEBTSHRCYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 153 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116818957-B Method for detecting content of sodium pentachlorophenolic acid and metabolite thereof in live pig sample 中国农业科学院农业质量标准与检测技术研究所 2023-11-14 CN claimed
CN-116818957-A Method for detecting content of sodium pentachlorophenolic acid and metabolite thereof in live pig sample 中国农业科学院农业质量标准与检测技术研究所 2023-09-29 CN claimed
EP-3881993-B1 METHOD FOR IMPROVING THE COMPLIANCE WITH QUALITY SPECIFICATIONS OF CORK PRODUCED FROM QUERCUS SUBER BY APPLYING KAOLINITE TO THE SURFACE OF THE EXPOSED INNER BARK OF A TREE, AFTER EXTRACTING THE CORK PLANK C & D COMERCIO E IND DE CORTICA LDA (PT) 2022-08-31 EP claimed
CN-108072727-B Method for simultaneously determining residual quantity of 23 organochlorine pesticides in pseudo-ginseng 天士力医药集团股份有限公司 2021-05-11 CN claimed
EP-2255182-B1 METHOD OF MONITORING THE CONTAMINATION OF BARRELS LABORATOIRE EXCELL (FR) 2018-12-12 EP claimed
EP-2033751-B1 Method of treating cork or a cork-based material using an inert gas under a pressure strictly lower than 1 MPa. DIAM BOUCHAGE (FR) 2012-02-01 EP claimed
EP-2355964-A1 PROCESS FOR THE EXTRACTION OF UNDESIRABLE AROMATIC MOLECULES FROM CORK VIA A THERMO-HYDRO-MECHANICAL TREATMENT OF INSTANTANEOUS CONTROLLED PRESSURE DROP (DIC) OPTIONALLY IN SUCCESSIVE FORM (EDS) Universite De La Rochelle (FR) 2011-08-17 EP claimed
US-20110113868-A1 PROCESS OF MONITORING THE CONTAMINATION OF BARRELS LABORATOIRE EXCELL (FR) 2011-05-19 US claimed
EP-2255182-A1 METHOD OF MONITORING THE CONTAMINATION OF BARRELS Laboratoire Excell (FR) 2010-12-01 EP claimed
WO-2010040949-A1 PROCESS FOR THE EXTRACTION OF UNDESIRABLE AROMATIC MOLECULES FROM CORK VIA A THERMO-HYDRO-MECHANICAL TREATMENT OF INSTANTANEOUS CONTROLLED PRESSURE DROP (DIC) OPTIONALLY IN SUCCESSIVE FORM (EDS) UNIVERSITE DE LA ROCHELLE (FR) 2010-04-15 WO claimed
WO-2009103640-A1 METHOD OF MONITORING THE CONTAMINATION OF BARRELS LABORATOIRE EXCELL (FR) 2009-08-27 WO claimed
US-20090130254-A1 Process for Removal of Toxic or Undersirable Polyhalogenated Compounds in Beverages, Especially in Wine VECT'OEUR (SARL) (FR) 2009-05-21 US claimed
EP-2033751-A1 Method of treating cork or a cork-based material using an inert gas under a pressure strictly lower than 1 MPa. OENEO BOUCHAGE (FR) 2009-03-11 EP claimed
EP-1778396-A1 METHOD FOR ELIMINATING TOXIC OR UNDESIRABLE POLYHALOGENATED COMPOUNDS FROM DRINKS, ESPECIALLY WINE Vect'Oeur (Sarl) (FR) 2007-05-02 EP claimed
WO-2006024767-A1 METHOD FOR ELIMINATING TOXIC OR UNDESIRABLE POLYHALOGENATED COMPOUNDS FROM DRINKS, ESPECIALLY WINE VECT'OEUR (SARL) (FR) 2006-03-09 WO claimed
EP-0730830-B1 Process for the removal of undesired lipophilic contaminations and/or residues which are contained in beverages or vegetable preparations FLACHSMANN AG EMIL (CH) 2002-02-06 EP claimed
US-5476788-A Solid phase bioremediation methods using lignin-degrading fungi THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) 1995-12-19 US claimed
US-4346244-A Preparation of chloroalkoxybenzenes RHONE-POULENC INDUSTRIES (FR) 1982-08-24 US claimed
EP-3844076-B1 DECORATIVE CLOSURE FOR A CONTAINER VINVENTIONS USA LLC (US) 2026-03-11 EP disclosed
EP-0002493-A1 Process for the preparation of 4,6-dihalogeno-1,3,5-triazines BAYER AG (DE) 1979-06-27 EP disclosed