Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 1/20 | 0.44 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.39 |
| ▸ | CDK9 | P50750 | 2/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.38 |
| ▸ | WNT3A | P56704 | 2/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.36 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24892328 | 0.83 | MAPKAPK2 (0.43) | WNT3AMAPKAPK2 | |
| SCHEMBL29803411 | 0.83 | CCNT1 (0.49) | CCNT1CDK9HDAC4HDAC6BRAF | |
| SCHEMBL171560 | 0.79 | P4HA1 (0.54) | WNT3AP2RY14SIGMAR1GABRPGABRD | |
| SCHEMBL24891691 | 0.77 | DYRK1A (0.48) | HCAR3WNT3ATSHR | |
| SCHEMBL4746022 | 0.72 | QDPR (0.62) | P2RY14SIGMAR1GABRPGABRDGABRA1 | |
| SCHEMBL24891690 | 0.71 | GRM1 (0.49) | WNT3A | |
| SCHEMBL24892089 | 0.71 | WNT3A (0.43) | CCNT1CDK9WNT3ATSHRMAPKAPK2 | |
| SCHEMBL30182219 | 0.71 | WNT3A (0.43) | CCNT1CDK9WNT3ATSHRMAPKAPK2 | |
| SCHEMBL24891851 | 0.71 | WNT3A (0.43) | WNT3ATSHRMAPKAPK2 | |
| SCHEMBL5225955 | 0.70 | HDAC1 (0.51) | HDAC4HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023287736-A1 | NOVEL BIS-AMIDE CONTAINING COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2023-01-19 | — | — | WO | disclosed |